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Articles Published Processes
4/18/2019 5:48:09 AM | Browse: 1092 | Download: 1889
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Received |
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2019-02-21 03:46 |
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Peer-Review Started |
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2019-02-21 07:21 |
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To Make the First Decision |
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2019-03-06 01:52 |
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Return for Revision |
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2019-03-06 02:13 |
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Revised |
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2019-03-10 14:40 |
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Second Decision |
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2019-03-15 09:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-03-16 17:39 |
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Articles in Press |
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2019-03-16 17:39 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-03-31 21:00 |
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Typeset the Manuscript |
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2019-04-17 00:54 |
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Publish the Manuscript Online |
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2019-04-18 05:48 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Extract of Cycas revoluta Thunb. enhances inhibitory effect of 5-fluorouracil on gastric cancer cells by AKT-mTOR pathway
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xing-Liang Cui, Ke-Ji Li, Hai-Xia Ren, Yong-Jian Zhang, Xiao-Dong Liu, Bao-Guo Bu and Lei Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Lei Wang, MA, MSc, Associate Professor, Department of Pathology, Medical College of Hebei University of Engineering, No. 42 Congtai Road, Handan 056000, Hebei Province, China. wangleinv1975@126.com |
| Key Words |
Gastric cancer; 5-fluorouracil; Cycas revolute Thunb.; Apoptosis |
| Core Tip |
5-fluorouracil (5-Fu) is one of the effective treatments for gastric cancer, one of the most common and deadly malignancies around the world. However, the effect of 5-Fu is limited by the drug resistance of gastric cancer. Here we reported that natural extract of Cycas revolute Thunb. could effectively inhibit cell growth, migration and invasion in gastric cancer. Furthermore, it could be used with 5-Fu to enhance its anti-cancer effect by AKT-mTOR pathway. |
| Publish Date |
2019-04-18 05:48 |
| Citation |
Cui XL, Li KJ, Ren HX, Zhang YJ, Liu XD, Bu BG, Wang L. Extract of Cycas revoluta Thunb. enhances inhibitory effect of 5-fluorouracil on gastric cancer cells by AKT-mTOR pathway. World J Gastroenterol 2019; 25(15): 1854-1864 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i15/1854.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i15.1854 |
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