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8/26/2019 10:16:55 AM | Browse: 117 | Download: 169
Publication Name World Journal of Stem Cells
Manuscript ID 46727
Country/Territory China
2019-02-21 01:38
Peer-Review Started
2019-02-22 09:25
To Make the First Decision
2019-06-05 06:47
Return for Revision
2019-06-06 04:12
2019-06-12 08:00
Second Decision
2019-06-14 14:59
Accepted by Journal Editor-in-Chief
2019-06-15 01:29
Accepted by Company Editor-in-Chief
2019-06-20 21:40
Articles in Press
2019-06-20 21:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-06-30 20:46
Typeset the Manuscript
2019-08-22 12:23
Publish the Manuscript Online
2019-08-26 10:16
ISSN 1948-0210 (online)
Open Access This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Linking stemness with colorectal cancer initiation, progression, and therapy
Manuscript Source Invited Manuscript
All Author List Deepak Narayanan Iyer, Wai-Yan Sin and Lui Ng
Author(s) ORCID Number
Deepak Narayanan Iyer http://orcid.org/0000-0002-8050-6647
Wai-Yan Sin http://orcid.org/0000-0003-2082-822X
Lui Ng http://orcid.org/0000-0002-9010-2654
Funding Agency and Grant Number
Corresponding author Lui Ng, PhD, Research Assistant Professor, Department of Surgery, The University of Hong Kong, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Hong Kong., Pokfulam NA, China. luing@hku.hk
Keywords Cancer stem cell; Colorectal cancer; Tumor microenvironment; Metastasis; Extracellular matrix; Tumor heterogeneity
Core Tip With the advancement of technology, the importance of deciphering the roles of stem cells in the normal and malignant intestinal biology has grown tremendously. Aided by several molecular and environmental factors, evidence suggests that the colorectal cancer stem cells exploit the intestinal cellular framework causing the development and spread of the disease, simultaneously promoting a poor prognosis through drug resistance and recurrence-based events. Only by a better understanding of the biology of these cells, can there be an improvement in the strategies associated with clinical monitoring and therapeutic targeting required for disease management.
Publish Date 2019-08-26 10:16
Citation Iyer DN, Sin WY, Ng L. Linking stemness with colorectal cancer initiation, progression, and therapy. World J Stem Cells 2019; 11(8):519-534
Url https://www.wjgnet.com/1948-0210/full/v11/i8/519.htm
DOI https://dx.doi.org/10.4252/wjsc.v11.i8.519
Full Article (PDF) WJSC-11-519.pdf
Full Article (Word) WJSC-11-519.docx
Manuscript File FP6888_de5_CE1MS-edit2.docx
Answering Reviewers 46727-Answering reviewers.pdf
Audio Core Tip 46727-Audio core tip.mp3
Conflict-of-Interest Disclosure Form 46727-Conflict-of-interest statement.pdf
Copyright License Agreement 46727-Copyright license agreement.pdf
Peer-review Report 46727-Peer-review(s).pdf
Journal Editor-in-Chief Review Report 46727-Journal editor-in-chief review report.pdf
Scientific Misconduct Check 46727-Scientific misconduct check.pdf
Scientific Editor Work List 46727-Scientific editor work list.pdf