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Articles Published Processes
5/6/2019 10:43:10 AM | Browse: 796 | Download: 1192
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Received |
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2019-02-25 01:23 |
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Peer-Review Started |
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2019-02-26 00:29 |
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To Make the First Decision |
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2019-03-14 00:14 |
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Return for Revision |
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2019-03-19 02:47 |
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Revised |
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2019-03-20 15:57 |
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Second Decision |
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2019-03-28 00:53 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-04-09 20:59 |
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Articles in Press |
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2019-04-09 20:59 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-04-16 17:08 |
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Typeset the Manuscript |
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2019-05-06 04:44 |
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Publish the Manuscript Online |
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2019-05-06 10:43 |
| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Rituximab-induced IgG hypogammaglobulinemia in children with nephrotic syndrome and normal pre-treatment IgG values
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Pierluigi Marzuillo, Stefano Guarino, Tiziana Esposito, Anna Di Sessa, Sara Immacolata Orsini, Daniela Capalbo, Emanuele Miraglia del Giudice and Angela La Manna |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Pierluigi Marzuillo, MD, PhD, Doctor, Postdoc, Postdoctoral Fellow, Department of Woman, Child and of General and Specialized Surgery, Università degli Studi della Campania “Luigi Vanvitelli”, Via Luigi De Crecchio 2, Naples 80138, Italy. pierluigi.marzuillo@gmail.com |
| Key Words |
Nephrotic syndrome; Rituximab; IgG hypogammaglobulinemia; Immunoglobulin |
| Core Tip |
It has been shown in pediatric patients with complicated nephrotic syndrome (NS) that rituximab (RTX) administration can induce persistent IgG hypogammaglobulinemia among subjects showing low basal IgG levels. Our case series shows that RTX can induce IgG hypogammaglobulinemia also in patients with pre-RTX IgG normal values and that persisting IgG hypogammaglobulinemia could be dose-dependent. When evaluating a patient with complicated NS and post-RTX IgG hypogammaglobulinemia, the IgG supplementation could not be needed because, until now, no severe infections have been detected and the possibility of adverse events related to IgG supplementation exists. |
| Publish Date |
2019-05-06 10:43 |
| Citation |
Marzuillo P, Guarino S, Esposito T, Di Sessa A, Orsini SI, Capalbo D, Miraglia del Giudice E, La Manna A. Rituximab-induced IgG hypogammaglobulinemia in children with nephrotic syndrome and normal pre-treatment IgG values. World J Clin Cases 2019; 7(9): 1021-1027 |
| URL |
https://www.wjgnet.com/2307-8960/full/v7/i9/1021.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v7.i9.1021 |
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