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5/20/2019 9:05:35 AM | Browse: 824 | Download: 1259
Publication Name World Journal of Gastroenterology
Manuscript ID 46936
Country China
Received
2019-02-28 01:07
Peer-Review Started
2019-03-01 05:15
To Make the First Decision
2019-04-08 01:12
Return for Revision
2019-04-08 07:02
Revised
2019-04-22 10:47
Second Decision
2019-04-30 09:49
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-03 12:03
Articles in Press
2019-05-03 12:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-05-08 02:32
Typeset the Manuscript
2019-05-20 00:32
Publish the Manuscript Online
2019-05-20 09:05
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Basic Study
Article Title Electroacupuncture at ST36 modulates gastric motility via vagovagal and sympathetic reflexes in rats
Manuscript Source Unsolicited Manuscript
All Author List Meng-Jiang Lu, Zhi Yu, Yan He, Bin Xu and Yin Yin
ORCID
Author(s) ORCID Number
Meng-Jiang Lu http://orcid.org/0000000186354659
Zhi Yu http://orcid.org/0000000291792618
Yan He http://orcid.org/0000-0002-9718-6483
Bin Xu http://orcid.org/0000000340063009
Yin Yin http://orcid.org/0000-0003-0516-7494
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China No.81373749
National Natural Science Foundation of China No.81673883
National Natural Science Foundation of China No.81574071
Corresponding Author Bin Xu, PhD, Professor, Key Laboratory of Integrated Acupuncture and Drugs Constructed, Nanjing University of Chinese Medicine, No. 138, Xianlin Road, Nanjing 210023, Jiangsu Province, China. xubin@njucm.edu.cn
Key Words Gastric motility; Electroacupuncture; Vagovagal reflex; Sympathetic nerve; Rats
Core Tip In this study, we measured intragastric pressure to observe the effect of electroacupuncture (EA) at ST36 on gastric motility at different time intervals. The role of the peripheral autonomic nervous system in EA was determined by the vagus nerve and splanchnic nerve severance model, as well as by detecting peripheral autonomic nerve discharge. M2/3 and β1/2 receptor knockout mouse models were further used to identify autonomic receptor subtypes specifically involved in the regulation of gastric motility. Finally, we studied the role of brainstem neurocircuits during EA at ST36 by detecting the dorsal motor nucleus of the vagus (DMV) neuron discharge and the effect of microinjection of γ-aminobutyric acid and glutamate to the DMV. Using these approaches, the role of vagovagal and sympathetic reflexes in regulating gastric motility by EA at ST36 was determined.
Publish Date 2019-05-20 09:05
Citation Lu MJ, Yu Z, He Y, Yin Y, Xu B. Electroacupuncture at ST36 modulates gastric motility via vagovagal and sympathetic reflexes in rats. World J Gastroenterol 2019; 25(19): 2315-2326
URL https://www.wjgnet.com/1007-9327/full/v25/i19/2315.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i19.2315
Full Article (PDF) WJG-25-2315.pdf
Full Article (Word) WJG-25-2315.docx
The ARRIVE Guidelines 46936-The-ARRIVE-Guidelines-revision.pdf
Manuscript File 46936-Review_Edited.docx
Answering Reviewers 46936-Answering reviewers.pdf
Audio Core Tip 46936-Audio core tip.wav
Biostatistics Review Certificate 46936-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 46936-Conflict-of-interest statement.pdf
Copyright License Agreement 46936-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 46936-Grant application form(s).pdf
Institutional Animal Care and Use Committee Approval Form or Document 46936-Institutional animal care and use committee statement.pdf
Institutional Review Board Approval Form or Document 46936-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 46936-Language certificate.pdf
Peer-review Report 46936-Peer-review(s).pdf
Scientific Misconduct Check 46936-Scientific misconduct check.pdf
Scientific Editor Work List 46936-Scientific editor work list.pdf