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Articles Published Processes
5/20/2019 9:05:35 AM | Browse: 958 | Download: 1752
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Received |
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2019-02-28 01:07 |
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Peer-Review Started |
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2019-03-01 05:15 |
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To Make the First Decision |
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2019-04-08 01:12 |
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Return for Revision |
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2019-04-08 07:02 |
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Revised |
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2019-04-22 10:47 |
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Second Decision |
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2019-04-30 09:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-03 12:03 |
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Articles in Press |
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2019-05-03 12:03 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-05-08 02:32 |
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Typeset the Manuscript |
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2019-05-20 00:32 |
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Publish the Manuscript Online |
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2019-05-20 09:05 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Electroacupuncture at ST36 modulates gastric motility via vagovagal and sympathetic reflexes in rats
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Meng-Jiang Lu, Zhi Yu, Yan He, Bin Xu and Yin Yin |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
No.81373749 |
| National Natural Science Foundation of China |
No.81673883 |
| National Natural Science Foundation of China |
No.81574071 |
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| Corresponding Author |
Bin Xu, PhD, Professor, Key Laboratory of Integrated Acupuncture and Drugs Constructed, Nanjing University of Chinese Medicine, No. 138, Xianlin Road, Nanjing 210023, Jiangsu Province, China. xubin@njucm.edu.cn |
| Key Words |
Gastric motility; Electroacupuncture; Vagovagal reflex; Sympathetic nerve; Rats |
| Core Tip |
In this study, we measured intragastric pressure to observe the effect of electroacupuncture (EA) at ST36 on gastric motility at different time intervals. The role of the peripheral autonomic nervous system in EA was determined by the vagus nerve and splanchnic nerve severance model, as well as by detecting peripheral autonomic nerve discharge. M2/3 and β1/2 receptor knockout mouse models were further used to identify autonomic receptor subtypes specifically involved in the regulation of gastric motility. Finally, we studied the role of brainstem neurocircuits during EA at ST36 by detecting the dorsal motor nucleus of the vagus (DMV) neuron discharge and the effect of microinjection of γ-aminobutyric acid and glutamate to the DMV. Using these approaches, the role of vagovagal and sympathetic reflexes in regulating gastric motility by EA at ST36 was determined. |
| Publish Date |
2019-05-20 09:05 |
| Citation |
Lu MJ, Yu Z, He Y, Yin Y, Xu B. Electroacupuncture at ST36 modulates gastric motility via vagovagal and sympathetic reflexes in rats. World J Gastroenterol 2019; 25(19): 2315-2326 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i19/2315.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i19.2315 |
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