Publication Name	World Journal of Clinical Infectious Diseases
Manuscript ID	4739
Country	Italy

Received	2013-07-20 09:05
Peer-Review Started	2013-07-22 19:12
To Make the First Decision	2013-09-02 16:26
Return for Revision	2013-09-03 21:32
Revised	2013-09-16 23:04
Second Decision	2013-11-15 19:03
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-16 01:31
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-21 14:24
Publish the Manuscript Online	2013-11-26 21:56

ISSN	2220-3176 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Infectious Diseases
Manuscript Type	Review
Article Title	Microbial translocation, residual viremia and immune senescence in the pathogenesis of HIV-1 infection
Manuscript Source	Invited Manuscript
All Author List	Alessandra Fantauzzi, Francesca Falasca, Gabriella d’Ettorre, Eugenio Nelson Cavallari, Ombretta Turriziani, Vincenzo Vullo and Ivano Mezzaroma
Funding Agency and Grant Number
Corresponding Author	Ivano Mezzaroma, MD, Department of Clinical Medicine, University of Rome, Viale dell’Università 37, 00185 Rome, Italy. ivano.mezzaroma@uniroma1.it
Key Words	Human immunodeficiency virus-1; Combined antiretroviral therapy; Immune activation; Microbial translocation; Residual viremia; Immune senescence
Core Tip	The aim of this review was to summarize the most relevant mechanisms in human immunodeficiency virus-1 pathogenesis by focusing on the role of microbial translocation, residual viremia, and immune senescence or “inflammaging” in disease progression to full-blown AIDS. Moreover, the impact of antiretroviral therapy on these mechanisms was investigated.
Publish Date	2013-11-26 21:56
Citation	Fantauzzi A, Falasca F, d’Ettorre G, Cavallari EN, Turriziani O, Vullo V, Mezzaroma I. Microbial translocation, residual viremia and immune senescence in the pathogenesis of HIV-1 infection. World J Clin Infect Dis 2013; 3(4): 47-57
URL	http://www.wjgnet.com/2220-3176/full/v3/i4/47.htm
DOI	http://dx.doi.org/10.5495/wjcid.v3.i4.47

Full Article (PDF)	WJCID-3-47.pdf
Manuscript File	4739-Review.docx
Answering Reviewers	4739-Answering reviewers.pdf
Copyright License Agreement	4739-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4739-Language certificate.pdf
Peer-review Report	4739-Peer review(s).pdf
Scientific Editor Work List	4739-Scientific editor work list.doc