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Articles Published Processes
6/14/2019 9:34:51 AM | Browse: 971 | Download: 1894
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Received |
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2019-03-14 01:38 |
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Peer-Review Started |
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2019-03-14 07:06 |
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To Make the First Decision |
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2019-03-27 05:37 |
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Return for Revision |
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2019-03-27 09:13 |
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Revised |
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2019-04-04 13:25 |
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Second Decision |
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2019-04-28 09:59 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-04-29 10:15 |
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Articles in Press |
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2019-04-29 10:15 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-05-04 22:56 |
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Typeset the Manuscript |
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2019-06-13 08:26 |
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Publish the Manuscript Online |
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2019-06-14 09:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which selected by an in-house editor and fully peer-reviewed by external reviewers. It distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Effects of early enteral nutrition on Th17/Treg and IL-23/IL-17 in septic patients
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jia-Kui Sun, Wen-Hao Zhang, Wen-Xiu Chen, Xiang Wang and Xin-Wei Mu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the National Natural Science Foundation of China |
No. 81701881 |
| the Nanjing Medical Science and Technology Development Foundation |
No. YKK15098 |
| the Nanjing Medical Science and Technology Development Foundation |
No. YKK17102 |
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| Corresponding Author |
Xiang Wang, MD, Doctor, Doctor, Department of Intensive Care Unit, Nanjing First Hospital, Nanjing Medical Universit, 68 Changle Road, Nanjing 210006, Jiangsu Province, China. njdrwx2016@163.com |
| Key Words |
Early enteral nutrition; Enteral nutrition; T helper lymphocytes; Th17/Treg cells; IL-23/IL-17 axis; Sepsis |
| Core Tip |
The aim of this prospective clinical trial was to investigate effects of early enteral nutrition (EEN) on Th17/Treg ratios and IL-23/IL-17 axis in septic patients. Patients were randomly divided into EEN or delayed enteral nutrition (DEN) groups. As a result, the Th17 percentages, Th17/Treg ratios, IL-17, IL-23, and IL-6 levels of the EEN group were lower than those of the DEN group on the 7th day after admission. In other words, EEN could regulate the imbalance of Th17/Treg ratios and suppress the IL-23/IL-17 axis during sepsis. Moreover, EEN could reduce the clinical severity but did not reduce the 28-d mortality of sepsis. |
| Publish Date |
2019-06-14 09:34 |
| Citation |
Sun JK, Zhang WH, Chen WX, Wang X, Mu XW. Effects of early enteral nutrition on Th17/Treg and IL-23/IL-17 in septic patients. World J Gastroenterol 2019; 25(22): 2799-2808 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i22/2799.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i22.2799 |
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