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Articles Published Processes
6/21/2019 3:42:23 AM | Browse: 771 | Download: 1593
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Received |
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2019-03-20 01:27 |
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Peer-Review Started |
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2019-03-20 06:00 |
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To Make the First Decision |
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2019-04-08 00:45 |
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Return for Revision |
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2019-04-08 07:16 |
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Revised |
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2019-05-07 07:44 |
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Second Decision |
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2019-05-08 08:32 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-05-08 16:07 |
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Articles in Press |
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2019-05-08 16:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-06-19 03:53 |
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Publish the Manuscript Online |
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2019-06-21 03:42 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Minireviews |
| Article Title |
Predicting systemic spread in early colorectal cancer: Can we do better?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Scarlet Fiona Brockmoeller and Nicholas Paul West |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Yorkshire Cancer Research |
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| Pelican Cancer Foundation |
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| National Institute for Health Research |
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| Pathological Society of Great Britain and Ireland |
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| Corresponding Author |
Nicholas Paul West, BSc, MBChB, PhD, Doctor, Doctor, Senior Lecturer, Pathology and Data Analytics, University of Leeds, Level 4 Wellcome Trust Brenner building, St. James’s University Hospital, Beckett Street, Leeds LS9 7TF, United Kingdom. n.p.west@leeds.ac.uk |
| Key Words |
Early colorectal cancer; Bowel cancer screening; Local resection; Major resection; Morphological risk factors; Conventional histopathology parameters; Novel histopathology parameters; Risk stratification models; Digital pathology |
| Core Tip |
Since the implementation of national bowel cancer screening programmes we have seen a three-fold increase in early colorectal cancers but how these lesion should surgical managed is currently unclear. Conventional histopathological parameters such as tumour grading or lymphovascular invasion have been shown to be predictive of lymph node metastasis but the inter- and intra-observer variation in reporting is significant. This review present the various conventional histopathological risk factors for predicting systemic spread in pT1 colorectal cancer and introduces novel quantitative variables and multivariable risk models that could be used to better define the optimal treatment of this increasingly common disease. |
| Publish Date |
2019-06-21 03:42 |
| Citation |
Brockmoeller SF, West NP. Predicting systemic spread in early colorectal cancer: Can we do better? World J Gastroenterol 2019; 25(23): 2887-2897 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i23/2887.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i23.2887 |
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