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6/28/2019 12:22:27 PM | Browse: 224 | Download: 273
Publication Name World Journal of Gastroenterology
Manuscript ID 47672
Country/Territory Spain
Received
2019-03-22 02:00
Peer-Review Started
2019-03-22 07:27
To Make the First Decision
2019-04-11 08:57
Return for Revision
2019-04-12 02:19
Revised
2019-05-06 17:26
Second Decision
2019-05-17 09:06
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-05-18 12:43
Articles in Press
2019-05-18 12:43
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2019-06-27 08:20
Publish the Manuscript Online
2019-06-28 12:22
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology and Hepatology
Manuscript Type Minireviews
Article Title Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease
Manuscript Source Invited Manuscript
All Author List Jose M Mato, Cristina Alonso, Mazen Noureddin and Shelly C Lu
ORCID
Author(s) ORCID Number
Jose M Mato http://orcid.org/0000-0003-1264-3153
Cristina Alonso http://orcid.org/0000-0002-2019-678X
Mazen Noureddin http://orcid.org/0000-0003-2127-2040
Shelly C Lu http://orcid.org/0000-0003-2128-5407
Funding Agency and Grant Number
Corresponding author Jose M Mato, PhD, Director, Professor, CIC bioGUNE, Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd), Technology Park of Bizkaia, Derio 48160, Bizkaia, Spain. director@cicbiogune.es
Keywords S-adenosylmethionine; Methionine adenosyltransferase; Lipid metabolism; Multiomics; Lipidomics; Nonalcoholic steatohepatitis; One-carbon metabolism; Very low-density lipoproteins; Steatosis; Precision medicine
Core Tip Nonalcoholic fatty liver disease (NAFLD) is a heterogeneous and complex disease that is imprecisely diagnosed by liver biopsy. The advent of metabolomics has shown that NAFLD progression from simple steatosis to nonalcoholic steatohepatitis (NASH) associates with profound alterations in liver and serum lipidomic signatures that are good indicators of the disease’s development and progression. Lipidomics has also permitted the classification of NAFLD patients into different subtypes corresponding to the main alteration(s) leading, in each case, to the initiation and progression of NASH based on the identification of specific lipid signatures, opening the door to the development of precise NASH treatments.
Publish Date 2019-06-28 12:22
Citation Mato JM, Alonso C, Noureddin M, Lu SC. Biomarkers and subtypes of deranged lipid metabolism in non-alcoholic fatty liver disease. World J Gastroenterol 2019; 25(24): 3009-3020
Url https://www.wjgnet.com/1007-9327/full/v25/i24/3009.htm
DOI https://dx.doi.org/10.3748/wjg.v25.i24.3009
Full Article (PDF) WJG-25-3009.pdf
Full Article (Word) WJG-25-3009.docx
Manuscript File 47672-Review.docx
Answering Reviewers 47672-Answering reviewers.pdf
Audio Core Tip 47672-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 47672-Conflict-of-interest statement.pdf
Copyright License Agreement 47672-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate 47672-Language certificate.pdf
Peer-review Report 47672-Peer-review(s).pdf
Scientific Misconduct Check 47672-Google-MA RY-1.png
Scientific Misconduct Check 47672-Google-MA RY-2.png
Scientific Misconduct Check 47672-Scientific misconduct check.pdf
Scientific Editor Work List 47672-Scientific editor work list.pdf