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Articles Published Processes
6/14/2019 9:34:51 AM | Browse: 625 | Download: 857
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Received |
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2019-03-27 06:29 |
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Peer-Review Started |
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2019-03-27 06:58 |
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To Make the First Decision |
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2019-04-17 00:15 |
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Return for Revision |
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2019-04-17 03:47 |
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Revised |
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2019-04-22 06:55 |
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Second Decision |
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2019-04-28 10:06 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-04-29 10:12 |
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Articles in Press |
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2019-04-29 10:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-05-20 18:35 |
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Typeset the Manuscript |
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2019-06-13 08:25 |
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Publish the Manuscript Online |
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2019-06-14 09:34 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Basic Study |
| Article Title |
Sp1 contributes to overexpression of stanniocalcin 2 through regulation of promoter activity in colon adenocarcinoma
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ji-Bin Li, Zhe-Xian Liu, Rui Zhang, Si-Ping Ma, Tao Lin, Yan-Xi Li, Shi-Hua Yang, Wan-Chuan Zhang and Yong-Peng Wang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of Liaoning Province, China |
20180550769 |
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| Corresponding Author |
Yong-Peng Wang, MD, Director, Department of Colorectal Surgery, Cancer Hospital of China Medical University, NO. 44, Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China. zzzrrr1234@sina.com |
| Key Words |
Transcription factor Sp1; Stanniocalcin 2; Overexpression; Promoter activity; Colon adenocarcinoma |
| Core Tip |
This study demonstrated that stanniocalcin 2 (STC2) was overexpressed in colon adenocarcinoma (COAD), besides the high expression of STC2 predicted poor prognosis. The promoter of STC2 in COAD was hyper-methylation, and the transcription factor Sp1 was essential to the expression of STC2. These findings provide new insights into the mechanism of oncogenic function of STC2 in COAD. |
| Publish Date |
2019-06-14 09:34 |
| Citation |
Li JB, Liu ZX, Zhang R, Ma SP, Lin T, Li YX, Yang SH, Zhang WC, Wang YP. Sp1 contributes to overexpression of stanniocalcin 2 through regulation of promoter activity in colon adenocarcinoma. World J Gastroenterol 2019; 25(22): 2776-2787 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i22/2776.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i22.2776 |
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