| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Gut microbiota contributes to the distinction between two traditional Chinese medicine syndromes of ulcerative colitis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Ya-Li Zhang, Li-Ting Cai, Jun-Yi Qi, Yun-Zheng Lin, Dai-Yan Cheng, Na Jiao, You-Lan Chen, Lie Zheng, Bei-Bei Wang, Li-Xin Zhu, Zhi-Peng Tang and Rui-Xin Zhu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Natural Science Foundation of China |
81704009 |
| Natural Science Foundation of China |
81873253，81573892，81770571 ，41530105，81774152 |
| the Shanghai Committee of Science and Technology |
16ZR1449800 |
| the University at Buffalo Community of Excellence in Genome, Environment and Microbiome |
(GEM) |
|
| Corresponding Author |
Zhi-Peng Tang, PhD, Doctor, Doctor, Professor, Institute of Digestive Diseases, Longhua Hospital, Shanghai University of Traditional Chinese Medicine, 725 Wanping Road, Shanghai 200032, China. zhipengtang@sohu.com |
| Key Words |
Ulcerative colitis; Intestinal microbiota; Pi-Xu-Shi-Yun syndrome; Da-Chang-Shi-Re syndrome; Traditional Chinese medicine |
| Core Tip |
Ulcerative colitis (UC) is considered to be closely associated with alteration of intestinal microorganisms. In traditional Chinese medicine (TCM) theory, UC can be divided into Pi-Xu-Shi-Yun syndrome (syndrome of spleen deficiency and dampness, PXSY) and Da-Chang-Shi-Re syndrome (syndrome of dampness-heat in the large intestine, DCSR). This study showed that the gut microbiota was different between patients with PXSY syndrome and those with DCSR syndrome. The genus Streptococcus was significantly more abundant in DCSR patients than in PXSY patients, while Lachnoclostridium was increased in PXSY patients. Our study suggests that the gut microbiota contributes to the distinction between two TCM syndromes of UC. |
| Publish Date |
2019-07-06 06:23 |
| Citation |
Zhang YL, Cai LT, Qi JY, Lin YZ, Dai YC, Jiao N, Chen YL, Zheng L, Wang BB, Zhu LX, Zhu RX, Tang ZP. Gut microbiota contributes to the distinction between two traditional Chinese medicine syndromes of ulcerative colitis. World J Gastroenterol 2019; 25(25): 3242-3255 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i25/3242.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i25.3242 |
