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Articles Published Processes
1/11/2020 12:25:00 AM | Browse: 718 | Download: 949
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Received |
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2019-05-06 00:38 |
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Peer-Review Started |
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2019-05-08 00:43 |
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To Make the First Decision |
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2019-09-09 08:37 |
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Return for Revision |
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2019-09-10 08:20 |
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Revised |
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2019-11-26 18:56 |
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Second Decision |
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2019-12-11 08:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-12-15 05:00 |
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Articles in Press |
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2019-12-15 05:00 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-01-03 07:36 |
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Publish the Manuscript Online |
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2020-01-11 00:25 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, Research & Experimental |
| Manuscript Type |
Basic Study |
| Article Title |
Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Juliana Souza Vieira, Emanuelle Juliana Cunha, Juliana Feltrin de Souza, Luis Henrique Koeler Chaves, Jessica Lakes de Souza and Allan Fernando Giovanini |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Allan Fernando Giovanini, PhD, Associate Professor, Dentistry, Positivo University, R. Prof. Pedro Viriato Parigot de Souza, 5300, Campo Comprido, Curitiba 81280-330, Brazil. afgiovanini@gmail.com |
| Key Words |
Alendronate; Bone development; Epiphyseal plate; Bone morphogentic protein-2; Transforming growth factor-β1; |
| Core Tip |
This is the first study that addresses the likely action of alendronate in appendicular bone development. Through of macroscopic, immunohistochemical and histological analysis, we revealed that alendronatemay impairs the bone growth, since alters the usual development of epiphyseal plate associated to changes in the immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2. |
| Publish Date |
2020-01-11 00:25 |
| Citation |
Vieira JS, Cunha EJ, de Souza JF, Chaves LHK, de Souza JL, Giovanini AF. Alendronate disturbs femoral growth due to changes during immunolocalization of transforming growth factor-β1 and bone morphogenetic protein-2 in epiphyseal plate. World J Exp Med 2020; 10(1): 1-9 |
| URL |
https://www.wjgnet.com/2220-315x/full/v10/i1/1.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v10.i1.1 |
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