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Articles Published Processes
9/21/2019 7:11:41 AM | Browse: 989 | Download: 2350
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Received |
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2019-04-30 00:50 |
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Peer-Review Started |
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2019-04-30 08:19 |
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To Make the First Decision |
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2019-05-31 00:54 |
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Return for Revision |
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2019-06-06 00:50 |
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Revised |
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2019-06-12 18:18 |
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Second Decision |
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2019-07-12 10:08 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-07-19 15:40 |
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Articles in Press |
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2019-07-19 15:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-09-17 01:29 |
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Publish the Manuscript Online |
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2019-09-21 07:11 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Meta-Analysis |
Article Title |
Gastric neuroendocrine neoplasms type 1: A systematic review and meta-analysis
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Manuscript Source |
Invited Manuscript |
All Author List |
Apostolos V Tsolakis, Athanasia Ragkousi, Miroslav Vujasinovic, Gregory Kaltsas and Kosmas Daskalakis |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Swedish Society of Medicine Post Doctoral Scholarship |
SLS-785911 |
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Corresponding Author |
Apostolos V Tsolakis, MD, PhD, Doctor, Doctor, Department of Oncology and Pathology, Karolinska Institutet, Stockholm, Sweden, Cancer Center Karolinska, CCK, Karolinska University Hospital Solna R8:04, Stockholm SE-17176, Sweden, Stockholm 171 76, Sweden. apobtsol@hotmail.com |
Key Words |
Gastric neuroendocrine neoplasms type 1; Meta-analysis; Lymph node metastasis; Tumor size; Invasion; Endoscopy |
Core Tip |
Hitherto, risk parameters predicting metastatic disease and the appropriateness of endoscopic vs surgical management of patients with gastric neuroendocrine neoplasms type 1 (GNENs1) have not been thoroughly investigated. The present systematic review and meta-analysis prove that locoregional lymph node (LN) metastases in GNENs1 are relatively rare (3.3%). Furthermore, tumour size ≥ 10 mm and the presence of the muscularis propria invasion are associated with an increased risk for LN metastasis. The latter finding suggests that endoscopic ultrasound investigation is very valuable in the work up of these lesions. Finally, surgical resection is linked to a lower risk for recurrence. |
Publish Date |
2019-09-21 07:11 |
Citation |
Tsolakis AV, Ragkousi A, Vujasinovic M, Kaltsas G, Daskalakis K. Gastric neuroendocrine neoplasms type 1: A systematic review and meta-analysis. World J Gastroenterol 2019; 25(35): 5376-5387 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i35/5376.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i35.5376 |
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