Publication Name	World Journal of Gastroenterology
Manuscript ID	4893
Country	Italy

Received	2013-07-31 10:22
Peer-Review Started	2013-07-31 16:39
First Decision by Editorial Office Director
Return for Revision	2013-08-27 10:07
Revised
Publication Fee Transferred
Second Decision by Editor	2013-11-13 10:09
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-11-13 14:27
Articles in Press
Edit the Manuscript by Language Editor	2013-11-25 23:05
Typeset the Manuscript	2013-12-11 13:39
Publish the Manuscript Online	2014-01-20 16:41

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Immunological alterations in hepatitis C virus infection
Manuscript Source	Invited Manuscript
All Author List	Vincenza Calvaruso and Antonio Craxì
Funding Agency and Grant Number
Corresponding Author	Vincenza Calvaruso, MD, PhD, Gastroenterologia and Epatologia, DIBIMIS, Università di Palermo, Piazza delle Cliniche n.2, 90127 Palermo, Italy. vincenza.calvaruso@unipa.it
Key Words	Hepatitis C virus; Immune disorders; Cytopenia; Extrahepatic manifestation; Autoantibody
Core Tip	Hepatitis C virus (HCV)-infected lymphoid tissue of the host represents a site for the persistence of HCV infection which exerts a chronic stimulus to the immune system, facilitating clonal B-lymphocyte expansion and consequent wide autoantibody production, including cryo- and non-cryo-precipitable immune complexes which may lead to organ- and non-organ-specific immunological alterations. This review outlines the principal aspects of such HCV-induced immunological alterations, focusing on the prevalence of these less characterized HCV extrahepatic manifestations.
Publish Date	2014-01-20 16:41
Citation	Calvaruso V, Craxì A. Immunological alterations in hepatitis C virus infection. World J Gastroenterol 2013; 19(47): 8916-8923
URL	http://www.wjgnet.com/1007-9327/full/v19/i47/8916.htm
DOI	http://dx.doi.org/10.3748/wjg.v19.i47.8916

Full Article (PDF)	WJG-19-8916.pdf
Manuscript File	4893-Review.docx
Answering Reviewers	4893-Answering reviewers.pdf
Copyright License Agreement	4893-Copyright assignment.pdf
Peer-review Report	4893-Peer reviewer(s).pdf
Scientific Editor Work List	4893-Scientific editor work list.doc