Publication Name	World Journal of Gastroenterology
Manuscript ID	4949
Country	Japan

Received	2013-08-05 10:22
Peer-Review Started	2013-08-05 18:48
First Decision by Editorial Office Director
Return for Revision	2013-08-30 08:29
Revised	2013-09-15 10:50
Publication Fee Transferred
Second Decision by Editor	2013-10-21 17:28
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director	2013-10-22 07:06
Articles in Press
Edit the Manuscript by Language Editor	2013-11-29 15:39
Typeset the Manuscript	2014-01-06 09:50
Publish the Manuscript Online	2014-01-19 14:17

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Long-term follow-up of ulcerative colitis patients treated on the basis of their cytomegalovirus antigen status
Manuscript Source	Invited Manuscript
All Author List	Toshihiro Inokuchi, Jun Kato, Sakiko Hiraoka, Hideyuki Suzuki, Asuka Nakarai, Tomoko Hirakawa, Mitsuhiro Akita, Sakuma Takahashi, Keita Harada, Hiroyuki Okada and Kazuhide Yamamoto
Funding Agency and Grant Number
Corresponding Author	Toshihiro Inokuchi, MD, Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama 700-8558, Japan. toshpi@yahoo.co.jp
Key Words	Ulcerative colitis; Cytomegalovirus; Cytomegalovirus antigenemia assay
Core Tip	Cytomegalovirus (CMV) reactivation has a deleterious effect in patients with ulcerative colitis (UC). Although antiviral therapy for CMV antigen-positive UC patients may be effective in the short-term, the long-term prognosis of UC patients with CMV treated by antiviral agents remains unknown. Our study revealed that positive CMV antigen status is likely to prolong time to remission in the treatment of flare-up of UC; however, long-term prognosis, including colectomy rate, was not affected by CMV antigen status treated with antiviral agents. Ganciclovir use is an independent factor for avoidance of colectomy in CMV antigen-positive UC patients.
Publish Date	2014-01-19 14:17
Citation	Inokuchi T, Kato J, Hiraoka S, Suzuki H, Nakarai A, Hirakawa T, Akita M, Takahashi S, Harada K, Okada H, Yamamoto K. Long-term follow-up of ulcerative colitis patients treated on the basis of their cytomegalovirus antigen status. World J Gastroenterol 2014; 20(2): 509-517
URL	http://www.wjgnet.com/1007-9327/full/v20/i2/509.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i2.509

Full Article (PDF)	WJG-20-509.pdf
Full Article (Word)	WJG-20-509.doc
Manuscript File	4949-Review.docx
Answering Reviewers	4949-Answering reviewers.pdf
Copyright License Agreement	4949-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	4949-Language certificate.pdf
Peer-review Report	4949-Peer reviewer(s).pdf
Scientific Editor Work List	4949-Scientific editor work list.doc