Publication Name	World Journal of Gastrointestinal Pathophysiology
Manuscript ID	49602
Country	United States

Received	2019-06-04 01:28
Peer-Review Started	2019-06-06 10:41
To Make the First Decision	2019-09-02 00:50
Return for Revision	2019-09-02 02:05
Revised	2019-09-06 21:41
Second Decision	2019-09-20 07:47
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2019-09-22 20:59
Articles in Press	2019-09-22 20:59
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2019-10-14 01:55
Publish the Manuscript Online	2019-10-15 09:53

ISSN	2150-5330 (online)
Open Access	This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Neutropenic enterocolitis: A clinico-pathological review
Manuscript Source	Unsolicited Manuscript
All Author List	Rong Xia and Xuchen Zhang
ORCID	Author(s) ORCID Number Rong Xia http://orcid.org/000-0003-2445-8246 Xuchen Zhang http://orcid.org/0000-0002-1484-4672
Funding Agency and Grant Number
Corresponding Author	Xuchen Zhang, MD, PhD, Associate Professor, Department of Pathology, Yale University School of Medicine, 310 Cedar Street, PO Box 208023, New Haven, CT 06510, United States. xuchen.zhang@yale.edu
Key Words	Neutropenic enterocolitis; Typhlitis; Chemotherapy; Neutropenia; ;
Core Tip	Neutropenic enterocolitis (NE) is a predominantly cecum-based disease with high mortality seen in patients post chemotherapy. The pathogenesis of NE is still poorly understood. The clinical presentation is characterized as ileocolonic inflammation and bowel wall thickening in patients with neutropenia, fever, and abdominal pain. The pathological features of NE include patchy necrosis, hemorrhage, ulcer, edema, perforation, infiltrating organisms, and characteristically, depletion of inflammatory cells (neutrophils). High clinical and histological diagnostic discordance rate exists. High index of clinical suspicion and timely diagnosis are critical for patient appropriate treatment and improvement of survival.
Publish Date	2019-10-15 09:53
Citation	Xia R, Zhang X. Neutropenic enterocolitis: A clinico-pathological review. World J Gastrointest Pathophysiol 2019; 10(3): 36-41
URL	https://www.wjgnet.com/2150-5330/full/v10/i3/36.htm
DOI	https://dx.doi.org/10.4291/wjgp.v10.i3.36

Full Article (PDF)	WJGP-10-36.pdf
Full Article (Word)	WJGP-10-36.docx
Manuscript File	49602-Review.docx
Answering Reviewers	49602-Answering reviewers.pdf
Audio Core Tip	49602-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	49602-Conflict-of-interest statement.pdf
Copyright License Agreement	49602-Copyright license agreement.pdf
Peer-review Report	49602-Peer-review(s).pdf
Scientific Misconduct Check	49602-Scientific misconduct check.pdf
Scientific Editor Work List	49602-Scientific editor work list.pdf
CrossCheck Report	49602-CrossCheck report.pdf