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Articles Published Processes
9/10/2014 2:59:00 PM | Browse: 817 | Download: 1089
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Received |
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2013-08-06 10:38 |
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Peer-Review Started |
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2013-08-06 21:45 |
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To Make the First Decision |
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2013-09-09 14:24 |
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Return for Revision |
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2013-09-12 11:33 |
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Revised |
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2013-09-15 21:58 |
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Second Decision |
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2013-11-01 16:50 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-11-03 11:15 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-11-14 16:52 |
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Publish the Manuscript Online |
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2013-11-29 02:07 |
Category |
Oncology |
Manuscript Type |
Autobiography |
Article Title |
Tumor antigen and MHC expression in glioma cells for immunotherapeutic interventions
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Manuscript Source |
Invited Manuscript |
All Author List |
Christina Susanne Mullins, Alexander Walter, Michael Schmitt, Carl-Friedrich Classen and Michael Linnebacher |
Funding Agency and Grant Number |
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Corresponding Author |
Michael Linnebacher, PhD, Department of General Surgery, Molecular Oncology and Immunotherapy, University Hospital Rostock, Schillingallee 35, 18057 Rostock, Germany. michael.linnebacher@med.uni-rostock.de |
Key Words |
Tumor antigens; Glioblastoma multiforme; Major histocompatibility complex molecules; Tumor models; Cell lines |
Core Tip |
Expression of tumor-antigens and major histocompatibility complex (MHC)-machinery components was analyzed in a series of seven novel low-passage glioblastoma multiforme cell lines by flow cytometry in comparison to three commercially available standard lines. MHC class Ⅰ was always expressed, MHC class Ⅱ readily after interferon gamma treatment. All cell lines expressed at least two tumor antigens. No differences between newly-established and commercially available cell lines were observed. Since these novel cell lines are available in low-passages upon request, they are interesting tools for future development of immunotherapeutic strategies, associated screenings and the like. |
Publish Date |
2013-11-29 02:07 |
Citation |
Mullins CS, Walter A, Schmitt M, Classen CF, Linnebacher M. Tumor antigen and MHC expression in glioma cells for immunotherapeutic interventions. World J Immunol 2013; 3(3): 62-67 |
URL |
http://www.wjgnet.com/2219-2824/full/v3/i3/62.htm |
DOI |
http://dx.doi.org/10.5411/wji.v3.i3.62 |
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