Publication Name	World Journal of Immunology
Manuscript ID	4975
Country	Germany

Received	2013-08-06 10:38
Peer-Review Started	2013-08-06 21:45
To Make the First Decision	2013-09-09 14:24
Return for Revision	2013-09-12 11:33
Revised	2013-09-15 21:58
Second Decision	2013-11-01 16:50
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-11-03 11:15
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-11-14 16:52
Publish the Manuscript Online	2013-11-29 02:07

ISSN	2219-2824 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Oncology
Manuscript Type	Autobiography
Article Title	Tumor antigen and MHC expression in glioma cells for immunotherapeutic interventions
Manuscript Source	Invited Manuscript
All Author List	Christina Susanne Mullins, Alexander Walter, Michael Schmitt, Carl-Friedrich Classen and Michael Linnebacher
Funding Agency and Grant Number
Corresponding Author	Michael Linnebacher, PhD, Department of General Surgery, Molecular Oncology and Immunotherapy, University Hospital Rostock, Schillingallee 35, 18057 Rostock, Germany. michael.linnebacher@med.uni-rostock.de
Key Words	Tumor antigens; Glioblastoma multiforme; Major histocompatibility complex molecules; Tumor models; Cell lines
Core Tip	Expression of tumor-antigens and major histocompatibility complex (MHC)-machinery components was analyzed in a series of seven novel low-passage glioblastoma multiforme cell lines by flow cytometry in comparison to three commercially available standard lines. MHC class Ⅰ was always expressed, MHC class Ⅱ readily after interferon gamma treatment. All cell lines expressed at least two tumor antigens. No differences between newly-established and commercially available cell lines were observed. Since these novel cell lines are available in low-passages upon request, they are interesting tools for future development of immunotherapeutic strategies, associated screenings and the like.
Publish Date	2013-11-29 02:07
Citation	Mullins CS, Walter A, Schmitt M, Classen CF, Linnebacher M. Tumor antigen and MHC expression in glioma cells for immunotherapeutic interventions. World J Immunol 2013; 3(3): 62-67
URL	http://www.wjgnet.com/2219-2824/full/v3/i3/62.htm
DOI	http://dx.doi.org/10.5411/wji.v3.i3.62

Full Article (PDF)	WJI-3-62.pdf
Manuscript File	4975-Review.docx
Answering Reviewers	4975-Answering reviewers.pdf
Copyright License Agreement	4975-Copyright assignment.pdf
Institutional Review Board Approval Form or Document	Ethics_Committee_20130805233901.pdf
Non-Native Speakers of English Editing Certificate	4975-Language certificate.pdf
Peer-review Report	4975-Peer review(s).pdf
Scientific Editor Work List	4975-Scientific editor work list.doc