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Articles Published Processes
11/7/2019 1:35:59 AM | Browse: 792 | Download: 1856
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Received |
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2019-07-12 01:51 |
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Peer-Review Started |
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2019-07-12 06:36 |
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To Make the First Decision |
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2019-08-19 00:56 |
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Return for Revision |
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2019-08-20 07:57 |
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Revised |
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2019-10-10 18:35 |
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Second Decision |
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2019-10-16 12:21 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-10-17 06:29 |
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Articles in Press |
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2019-10-17 06:29 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-10-28 02:46 |
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Publish the Manuscript Online |
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2019-11-07 01:35 |
ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Surgery |
Manuscript Type |
Retrospective Study |
Article Title |
Bacterobilia in pancreatic surgery-conclusions for perioperative antibiotic prophylaxis
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Colin Markus Krueger, Ulrich Adam, Thomas Adam, Axel Kramer, Claus D Heidecke, Frank Makowiec and Hartwig Riediger |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Colin Markus Krueger, FACS, MD, PhD, Chief Physician, Postdoc, Surgeon, Department of Surgery, Immanuel Hospital Ruedersdorf, Seebad 82/83, Ruedersdorf b. BErlin 15562, Brandenburg, Germany. cm.krueger@immanuel.de |
Key Words |
Pancreatic surgery; Bacteriobilia; Antibiotic prophylaxis; Cholestasis; Cholangiopancreatography; Endoscopic retrograde |
Core Tip |
The aim of our retrospective study was to analyze the microbial profile of bacteriobilia in patients undergoing pancreatic head resection (n = 285). Patients with preoperative biliary drainage (PBD +) had a significantly elevated risk of bacteriobilia. In those cases, the contamination was polymicrobiotic. Enterococcus was significantly more frequent in PBD +. Our standard preoperative antibiotic prophylaxis reaches an overall sensitivity rate of 60% and a resistance rate of 25% in 342 bacteria. The antibiotic efficiency of Imipenem and Piperacillin/Tazobactam is significantly higher in PBD +. The data on polymicrobial colonization of the biliary tract may be useful for the decision on antibiotic treatment in case of postoperative infection until the final results from the intraoperative smear are available. A more potent alternative for prophylactic application, however, was not found among the examined antibiotics. |
Publish Date |
2019-11-07 01:35 |
Citation |
Krüger CM, Adam U, Adam T, Kramer A, Heidecke CD, Makowiec F, Riediger H. Bacterobilia in pancreatic surgery-conclusions for perioperative antibiotic prophylaxis. World J Gastroenterol 2019; 25(41): 6238-6247 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i41/6238.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i41.6238 |
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