BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
10/14/2019 10:47:07 AM | Browse: 903 | Download: 2533
 |
Received |
|
2019-06-18 06:25 |
|
Peer-Review Started |
|
2019-06-20 10:57 |
|
First Decision by Editorial Office Director |
|
2019-08-27 23:37 |
|
Return for Revision |
|
2019-09-02 07:55 |
|
Revised |
|
2019-09-06 11:24 |
 |
Publication Fee Transferred |
|
|
|
Second Decision by Editor |
|
2019-09-26 10:41 |
|
Second Decision by Editor-in-Chief |
|
|
|
Final Decision by Editorial Office Director |
|
2019-09-28 04:49 |
|
Articles in Press |
|
2019-09-28 04:49 |
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2019-10-14 07:41 |
|
Publish the Manuscript Online |
|
2019-10-14 10:47 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Hepatitis C virus clearance and less liver damage in patients with high cholesterol, low-density lipoprotein cholesterol and APOE ε4 allele
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Karina Gonzalez-Aldaco, Sonia Roman, Rafael Torres-Valadez, Claudia Ojeda-Granados, Luis Alberto Torres-Reyes and Arturo Panduro |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Programa para el Desarrollo Profesional Docente |
UDG-PTC-1422 |
| Consejo Nacional de Ciencia y Tecnología |
2017-01-5254 |
|
| Corresponding Author |
Arturo Panduro, MD, PhD, Professor, Research Scientist, Senior Scientist, Department of Molecular Biology in Medicine, Civil Hospital of Guadalajara Fray Antonio Alcalde/University of Guadalajara, Hospital # 278
Col. El Retiro,, Guadalajara 44280, Jalisco, Mexico. biomomed@cencar.udg.mx |
| Key Words |
Liver damage; Body mass index; Spontaneous hepatitis C virus clearance; Low-density lipoprotein; Cholesterol; |
| Core Tip |
Cholesterol is a metabolic regulator of the hepatitis C virus (HCV) life cycle. Genetic polymorphisms in the APOE gene can regulate cholesterol and modify the outcome of the HCV infection. Our findings suggest that APOE ε4 allele and low-density lipoprotein cholesterol (LDL-c) confer a protective effect in the course of the HCV infection in the context of high body mass index (BMI). Levels of LDL-c, BMI, and ALT may estimate the risk of chronicity in HCV-infected patients. An individualized therapy accounting the host´s genetic, environmental, and metabolic factors could aid in the clinical management of HCV infection, especially in populations with a high prevalence of overweight and obesity. |
| Publish Date |
2019-10-14 10:47 |
| Citation |
Gonzalez-Aldaco K, Roman S, Torres-Valadez R, Ojeda-Granados C, Torres-Reyes LA, Panduro A. Hepatitis C virus clearance and less liver damage in patients with high cholesterol, low-density lipoprotein cholesterol and APOE ε4 allele. World J Gastroenterol 2019; 25(38): 5826-5837 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i38/5826.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i38.5826 |
All content on this site: Copyright © 1993-2026 Baishideng Publishing Group Inc, its licensors, and contributors. All rights are reserved, including those for text and data mining, AI training, and similar technologies. For all open access content, the relevant licensing terms apply.
