ISSN |
1007-9327 (print) and 2219-2840 (online) |
Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Observational Study |
Article Title |
Analysis of 72 patients with colorectal high-grade neuroendocrine neoplasms from three Chinese hospitals
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Manuscript Source |
Invited Manuscript |
All Author List |
Zhi-Jie Wang, Ke An, Rui Li, Wei Shen, Man-dula Bao, Jin-Hua Tao, Jia-Nan Chen, Shi-Wen Mei, Hai-Yu Shen, Yun-bin Ma, Fu-qiang Zhao, Fang-ze Wei and Qian Liu |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Medicine and Health Technology Innovation Project of Chinese Academy of Medical Sciences |
No.2017-12M-1-006 |
China Cancer Research Foundation, Beijing Terry Fox Run Special Fund |
No.LC2017L03, No.LC2017A19 |
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Corresponding Author |
Qian Liu, MD, Chief Doctor, Professor, Surgeon, Teacher, Department of Colorectal Surgery, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union College, No. 17, Panjiayuan Nanli, Chaoyang District, Beijing 100021, China. fcwpumch@163.com |
Key Words |
Colon; Rectum; Neuroendocrine; Neoplasm; Metastasis; Prognosis |
Core Tip |
Colorectal high-grade neuroendocrine neoplasms (HGNENs) are aggressive malignancies with extremely low incidence. Many issues, such as their classification and therapy strategies, have been controversial for a long time. We conducted this study to delineate their clinicopathologic features and clinical outcomes. There is a trend to categorize colorectal HGNENs with good morphological differentiation as a subgroup different from high-grade neuroendocrine carcinomas in the newest World Health Organization classification. We introduced this classification into our study and compared the prognoses of different subgroups. |
Publish Date |
2019-09-12 08:50 |
Citation |
Wang ZJ, An K, Li R, Shen W, Bao MD, Tao JH, Chen JN, Mei SW, Shen HY, Ma YB, Zhao FQ, Wei FZ, Liu Q. Analysis of 72 patients with colorectal high-grade neuroendocrine neoplasms from three Chinese hospitals. World J Gastroenterol 2019; 25(34): 5197-5209 |
URL |
https://www.wjgnet.com/1007-9327/full/v25/i34/5197.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v25.i34.5197 |