BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
11/21/2019 8:36:03 AM | Browse: 869 | Download: 1206
 |
Received |
|
2019-07-05 00:43 |
|
Peer-Review Started |
|
2019-07-16 07:44 |
|
To Make the First Decision |
|
2019-08-21 00:24 |
|
Return for Revision |
|
2019-08-21 01:18 |
|
Revised |
|
2019-08-30 12:15 |
|
Second Decision |
|
2019-10-12 07:25 |
 |
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2019-10-15 20:53 |
|
Articles in Press |
|
2019-10-15 20:53 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
2019-11-11 07:14 |
|
Typeset the Manuscript |
|
2019-11-19 03:37 |
|
Publish the Manuscript Online |
|
2019-11-21 08:36 |
| ISSN |
1949-8454 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Review |
| Article Title |
Complex interactomes and post-translational modifications of the regulatory proteins HABP4 and SERBP1 suggest pleiotropic cellular functions
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Carolina Colleti, Talita Diniz Melo-Hanchuk, Flávia Moraes da Silva, Ângela Saito and Jörg Kobarg |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Conselho Nacional de Desenvolvimento Cientifico e Tecnológico |
302534/2017-2 |
|
| Corresponding Author |
Jörg Kobarg, PhD, Full Professor, Faculty of Pharmaceutical Sciences, University of Campinas, Rua Monteiro Lobato 255, Bloco F, Sala 3, Campinas 13083-862, Brazil. jorgkoba@unicamp.br |
| Key Words |
Cancer; Cell signaling; Regulatory protein; Protein interactions; Post-translational modifications; |
| Core Tip |
Intracellular hyaluronic acid binding protein 4 and serpin mRNA binding protein 1 are paralog human regulatory proteins that share 41% amino acid sequence identity. The characterization of their protein interactomes suggested their functional association to transcriptional regulation, mRNA metabolism and further in the cell’s DNA damage and stress responses. Their complex post-translation modifications, involving phosphorylation, arginine methylation and sumoylation, as well as their finely regulated sub-cellular localization to the nucleus and cytoplasm as well as to several cytoplasmic and nuclear granules suggest extensive functional regulation. This review discusses functional and structural aspects and emerging roles of these regulatory proteins in human cancer. |
| Publish Date |
2019-11-21 08:36 |
| Citation |
Colleti C, Melo-Hanchuk TD, Moraes da Silva FR, Saito A, Kobarg J. Complex interactomes and post-translational modifications of the regulatory proteins HABP4 and SERBP1 suggest pleiotropic cellular functions. World J Biol Chem 2019; 10(3): 44-64 |
| URL |
https://www.wjgnet.com/1949-8454/full/v10/i3/44.htm |
| DOI |
https://dx.doi.org/10.4331/wjbc.v10.i3.44 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
