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8/27/2014 4:41:00 PM | Browse: 988 | Download: 808
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Received |
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2013-08-10 21:40 |
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Peer-Review Started |
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2013-08-12 10:39 |
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To Make the First Decision |
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2013-09-09 14:23 |
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Return for Revision |
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2013-09-11 09:29 |
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Revised |
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Second Decision |
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2013-10-17 13:23 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-10-18 07:25 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2013-11-26 13:41 |
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Publish the Manuscript Online |
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2013-12-06 18:20 |
Category |
Biochemical Research Methods |
Manuscript Type |
Minireviews |
Article Title |
Lipidomic mass spectrometry and its application in neuroscience
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Manuscript Source |
Invited Manuscript |
All Author List |
Mabel Enriquez-Algeciras and Sanjoy K Bhattacharya |
Funding Agency and Grant Number |
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Corresponding Author |
Sanjoy K Bhattacharya, MTech, PhD, Bascom Palmer Eye Institute, Department of Biochemistry and Molecular Biology and Neuroscience Program, University of Miami, 1638 NW 10th Avenue, Suite 707A, Miami, FL 33136,United States. sbhattacharya@med.miami.edu |
Key Words |
Mass spectrometry; Lipidomics; Phospholipids; Serial signaling; Neuroscience |
Core Tip |
Mass spectrometry offers a degree of simplicity and sophistication to the biological sciences. In this review we are focusing on its application towards the analysis of lipids in neuroscience. Lipids have a variety of functions, they surround neurons, provide insulation for transmission of signals, an environment for facilitating motility and migration of astrocytes and other cell types, among many other functions. Recent advances in mass spectrometry have enabled quantification of lipids directly extracted from complex biological mixtures in the neuronal system with the help of databases, standardized instrument parameters and bioinformatics. In this review, we intend to highlight all recent efforts with an emphasis on its application to neuroscience. |
Publish Date |
2013-12-06 18:20 |
Citation |
Enriquez-Algeciras M, Bhattacharya SK. Lipidomic mass spectrometry and its application in neuroscience. World J Biol Chem 2013; 4(4): 102-110 |
URL |
http://www.wjgnet.com/1949-8454/full/v4/i4/102.htm |
DOI |
http://dx.doi.org/10.4331/wjbc.v4.i4.102 |
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