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Articles Published Processes
12/17/2019 7:13:45 AM | Browse: 1007 | Download: 1327
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Received |
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2019-08-03 00:16 |
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Peer-Review Started |
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2019-08-03 00:17 |
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To Make the First Decision |
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2019-09-29 03:06 |
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Return for Revision |
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2019-10-14 02:03 |
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Revised |
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2019-11-07 19:31 |
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Second Decision |
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2019-11-26 08:29 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-11-26 22:20 |
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Articles in Press |
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2019-11-26 22:20 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2019-12-12 06:26 |
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Publish the Manuscript Online |
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2019-12-17 07:13 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article which was selected byan in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author (s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Endocrinology & Metabolism |
| Manuscript Type |
Review |
| Article Title |
Complement activation in obesity, insulin resistance, and type 2 diabetes mellitus
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Kyumin Shim, Rayhana Begum, Catherine Yang and Hongbin Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Hongbin Wang, BPharm, MSc, PhD, Assistant Professor, Department of Biomedical and Pharmaceutical Sciences, California Northstate University College of Pharmacy, 9700 W Taron Dr., Elk Grove, CA 95757, United States. hongbin.wang@cnsu.edu |
| Key Words |
Inflammation; Complement activation; Metabolic disorders; Obesity; Insulin resistance; Type 2 diabetic mellitus |
| Core Tip |
Inflammatory reaction is involved in cardiometabolic diseases such as obesity, insulin resistance, and diabetes. The complement system, a key component of innate immunity, was viewed as the first line of defense against microbial. Recent research has come to appreciate that the complement system is involved in such diverse processes as clearance of the immune complexes, complementing immune functions, tissue regeneration, and metabolism. The review is to update the role of the activation of complement system and the progression of metabolic disorders. We provided a paradigm that targeting complement therapeutics could be one of possible routes to slow down diabetic complications. |
| Publish Date |
2019-12-17 07:13 |
| Citation |
Shim K, Begum R, Yang C, Wang H. Complement activation in obesity, insulin resistance, and type 2 diabetes mellitus. World J Diabetes 2020; 11(1): 1-12 |
| URL |
https://www.wjgnet.com/1948-9358/full/v11/i1/1.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v11.i1.1 |
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