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1/7/2020 7:47:48 AM | Browse: 926 | Download: 1170
Publication Name World Journal of Gastroenterology
Manuscript ID 51041
Country/Territory Germany
Received
2019-09-02 21:01
Peer-Review Started
2019-09-02 21:02
To Make the First Decision
2019-10-14 09:40
Return for Revision
2019-10-15 09:48
Revised
2019-12-04 22:55
Second Decision
2019-12-12 07:32
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-12-13 01:41
Articles in Press
2019-12-13 01:41
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-01-06 09:53
Publish the Manuscript Online
2020-01-07 07:47
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Prognostic value of serum microRNA-122 in hepatocellular carcinoma is dependent on coexisting clinical and laboratory factors
Manuscript Source Unsolicited Manuscript
All Author List Martin Franck, Kerstin Schuette, Peter Malfertheiner and Alexander Link
ORCID
Author(s) ORCID Number
Martin Franck http://orcid.org/0000-0001-6889-2955
Kerstin Schuette http://orcid.org/0000-0002-1724-3733
Peter Malfertheiner http://orcid.org/0000-0001-8439-9036
Alexander Link http://orcid.org/0000-0002-9514-4562
Funding Agency and Grant Number
Corresponding Author Alexander Link, MD, PhD, Academic Research, Associate Professor, Department of Gastroenterology, Hepatology and Infectious Diseases, Otto-von-Guericke University Magdeburg, Leipziger Str. 44, Magdeburg 39120, Germany. alexander.link@med.ovgu.de
Key Words Hepatocellular carcinoma; MicroRNA; Prognosis; MicroRNA-122; Influencing factors;
Core Tip Small non-coding RNAs are in focus of liver biomarker research. Here we confirm that the most abundant liver-specific microRNA-122 (miR-122) is a potential biomarker for liver injury and has potential value to predict the outcome of patients with hepatocellular carcinoma, but several influencing factors need to be taken into account while interpreting the miR-122 level. Besides clinical aspects, several coexisting factors like impairment of renal function, hemoglobin concentration, alpha-fetoprotein level and liver injury may strongly influence the circulating miR-122 level and potential clinical translational application of miR-122.
Publish Date 2020-01-07 07:47
Citation Franck M, Schütte K, Malfertheiner P, Link A. Prognostic value of serum microRNA-122 in hepatocellular carcinoma is dependent on coexisting clinical and laboratory factors. World J Gastroenterol 2020; 26(1): 86-96
URL https://www.wjgnet.com/1007-9327/full/v26/i1/86.htm
DOI https://dx.doi.org/10.3748/wjg.v26.i1.86
Full Article (PDF) WJG-26-86.pdf
Full Article (Word) WJG-26-86.docx
Manuscript File 51041-Review.docx
Answering Reviewers 51041-Answering reviewers.pdf
Audio Core Tip 51041-Audio core tip.m4a
Biostatistics Review Certificate 51041-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 51041-Conflict-of-interest statement.pdf
Copyright License Agreement 51041-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 51041-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 51041-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 51041-Language certificate.pdf
Supplementary Material 51041-Supplementary material.pdf
Peer-review Report 51041-Peer-review(s).pdf
Scientific Misconduct Check 51041-Scientific misconduct check.pdf
Scientific Editor Work List 51041-Scientific editor work list.pdf