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Articles Published Processes
11/28/2019 10:38:52 AM | Browse: 945 | Download: 1244
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Received |
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2019-08-30 07:33 |
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Peer-Review Started |
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2019-08-30 07:33 |
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To Make the First Decision |
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2019-10-14 09:09 |
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Return for Revision |
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2019-10-16 09:22 |
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Revised |
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2019-10-30 04:06 |
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Second Decision |
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2019-11-12 10:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-11-13 01:49 |
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Articles in Press |
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2019-11-13 01:49 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2019-11-24 23:31 |
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Typeset the Manuscript |
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2019-11-27 03:40 |
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Publish the Manuscript Online |
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2019-11-28 10:38 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Long noncoding RNA NALT1-induced gastric cancer invasion and metastasis via NOTCH signaling pathway
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hai-Yan Piao, Shuai Guo, Yue Wang and Jun Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Liaoning S&T Project |
20180550971 |
| Liaoning S&T Project |
20170520447 |
| CSCO-MERCK SERNO oncology research fund |
Y-MX2016-031 |
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| Corresponding Author |
Jun Zhang, MD, Doctor, Doctor, Gastric Cancer Department, LiaoNing Cancer Hospital & Institute, Xiaoheyan Road, Dadong District, Shenyang 110042, Liaoning Province, China. surgeonzhangjun@hotmail.com |
| Key Words |
Gastric cancer; Weighted gene coexpression network analysis; NALT1; NOTCH1; Cancer survival; |
| Core Tip |
TCGA and clinical data identified lncRNA NALT1 was associated with poor prognosis of gastric cancer (GC) and the possible mechanism was also studied. We downloaded the TCGA-STAD RNA-seq data and identified the differentially expressed lncRNAs. WGCNA was used to clarify the connection between modules and clinical information. We then chose lncRNA NALT1 as the hub-lncRNA of blue-module. NALT1 was overexpressed and promoted invasion and metastasis of GC. The over-expression of NALT1 was linked to poor prognosis in GC. The mechanism may be related to the regulation of NOTCH1 by NALT1 and its effect on the expression of NOTCH signaling pathway. |
| Publish Date |
2019-11-28 10:38 |
| Citation |
Piao HY, Guo S, Wang Y, Zhang J. Long noncoding RNA NALT1-induced gastric cancer invasion and metastasis via NOTCH signaling pathway. World J Gastroenterol 2019; 25(44): 6508-6526 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i44/6508.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i44.6508 |
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