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12/25/2019 11:24:44 AM | Browse: 670 | Download: 1057
Publication Name World Journal of Clinical Cases
Manuscript ID 51293
Country China
Received
2019-09-08 05:19
Peer-Review Started
2019-09-08 05:19
To Make the First Decision
Return for Revision
2019-11-11 23:06
Revised
2019-11-14 11:27
Second Decision
2019-11-26 10:08
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2019-11-26 17:28
Articles in Press
2019-11-26 17:28
Publication Fee Transferred
Edit the Manuscript by Language Editor
2019-12-12 06:58
Typeset the Manuscript
2019-12-23 06:21
Publish the Manuscript Online
2019-12-25 11:24
ISSN 2307-8960 (online)
Open Access This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Hematology
Manuscript Type Observational Study
Article Title Expression of interleukin-32 in bone marrow of patients with myeloma and its prognostic significance
Manuscript Source Unsolicited Manuscript
All Author List Gang Wang, Fang-Ying Ning, Jia-Heng Wang, Hai-Meng Yan, Hong-Wei Kong, Yu-Ting Zhang and Qiang Shen
ORCID
Author(s) ORCID Number
Gang Wang http://orcid.org/0000-0002-2483-1947
Fang-Ying Ning http://orcid.org/0000-0002-8362-944X
Jia-Heng Wang http://orcid.org/0000-0001-9378-2934
Hai-Meng Yan http://orcid.org/0000-0003-2837-2283
Hong-Wei Kong http://orcid.org/0000-0002-1293-3382
Yu-Ting Zhang http://orcid.org/0000-0001-3847-2937
Qiang Shen http://orcid.org/0000-0003-1242-3323
Funding Agency and Grant Number
Funding Agency Grant Number
Excellent Young Medical Talents from the Quzhou People’s Hospital
Corresponding Author Fang-Ying Ning, MD, Doctor, Department of Hematology, People’s Hospital of Hangzhou Medical College, Zhejiang Provincial People’s Hospital, NO .158 Shangtang Road, Xiacheng District, Hangzhou 310000, Zhejiang Province, China. ningfangying2011@163.com
Key Words Multiple myeloma; Interleukin-32; Minimal residual lesions; Progression-free survival; Overall survival; Prognosis
Core Tip Multiple myeloma (MM) is a heterogeneous disease with large differences in survival time from several months to 20 years, and its clinical manifestations are complex. There are many factors affecting the prognosis. International Staging System and Durie-Salmon staging has been established to assess the prognosis of the disease, but the accuracy of β2-microglobulin and albumin was controversial. In recent years, new prognostic indicators of MM are being continuously explored. Studies have shown that associated with renal function, degree of bone destruction, and hypercalcemia, which can reveal the prognosis of MM and predict the overall survival (OS). Moreover, minimal residual disease can also predict OS and progression-free survival in patients with MM. We collected the data from MM patients in our hospital, analyzed their clinical efficacy, follow-up results and laboratory examination indicators, and suggested that interleukin-32 can be used as an auxiliary indicator for post-treatment efficacy and prognosis assessment.
Publish Date 2019-12-25 11:24
Citation Wang G, Ning FY, Wang JH, Yan HM, Kong HW, Zhang YT, Shen Q. Expression of interleukin-32 in bone marrow of patients with myeloma and its prognostic significance. World J Clin Cases 2019; 7(24): 4234-4244
URL https://www.wjgnet.com/2307-8960/full/v7/i24/4234.htm
DOI https://dx.doi.org/10.12998/wjcc.v7.i24.4234
Full Article (PDF) WJCC-7-4234.pdf
Full Article (Word) WJCC-7-4234.docx
STROBE Statement 51293-STROBE-Statement-revision.pdf
Manuscript File 51293-Review-Webster JR.docx
Answering Reviewers 51293-Answering reviewers.pdf
Audio Core Tip 51293-Audio core tip.m4a
Biostatistics Review Certificate 51293-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 51293-Conflict-of-interest statement.pdf
Copyright License Agreement 51293-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 51293-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 51293-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 51293-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 51293-Language certificate.pdf
Peer-review Report 51293-Peer-review(s).pdf
Scientific Misconduct Check 51293-Scientific misconduct check.pdf
Scientific Editor Work List 51293-Scientific editor work list.pdf