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Articles Published Processes
4/15/2020 12:00:00 PM | Browse: 683 | Download: 1284
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Received |
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2019-12-21 07:51 |
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Peer-Review Started |
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2019-12-21 07:51 |
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To Make the First Decision |
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Return for Revision |
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2020-01-19 01:43 |
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Revised |
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2020-02-04 09:05 |
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Second Decision |
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2020-03-19 11:38 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-22 21:37 |
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Articles in Press |
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2020-03-22 21:37 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-13 17:43 |
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Publish the Manuscript Online |
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2020-04-15 12:00 |
ISSN |
1948-5204 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Basic Study |
Article Title |
LINC00511 promotes gastric cancer cell growth by acting as a ceRNA
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Chong-Bing Sun, Hong-Yi Wang, Xiao-Qing Han, Yong-Ning Liu, Meng-Chun Wang, Hong-Xia Zhang, You-Feng Gu and Xiao-Gang Leng |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Xiao-Gang Leng, MD, Attending Doctor, Department of Anorectal Surgery, Weifang People's Hospital, No. 151 Guangwen Street, Kuiwen District, Weifang 261041, Shandong Province, China. docxiaogang@163.com |
Key Words |
; Gastric cancer; Long noncoding RNAs; PDK4; miR-124-3p; LINC00511 |
Core Tip |
In this study, we aimed to determine whether the long noncoding RNAs LINC00511 exerted its carcinogenic function in gastric cancer (GC) via the miR-124-3p/PDK4 axis. First, we investigated the expression level of LINC00511 in GC cell lines, and we then examined the biological function of LINC00511 with functional assays. Next, we predicted and confirmed the interaction between LINC00511 and miR-124-3p. Furthermore, we further found that PDK4 was a downstream target of miR-124-3p. Finally, we concluded that LINC00511 plays an oncogenic role in GC by sponging miR-124-3p and targeting PDK4, indicating that LINC00511 may be a new molecular biomarker for GC. |
Publish Date |
2020-04-15 12:00 |
Citation |
Sun CB, Wang HY, Han XQ, Liu YN, Wang MC, Zhang HX, Gu YF, Leng XG. LINC00511 promotes gastric cancer cell growth by acting as a ceRNA. World J Gastrointest Oncol 2020; 12(4): 394-404 |
URL |
https://www.wjgnet.com/1948-5204/full/v12/i4/394.htm |
DOI |
https://dx.doi.org/10.4251/wjgo.v12.i4.394 |
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