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Articles Published Processes
2/28/2020 9:45:40 AM | Browse: 706 | Download: 706
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Received |
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2019-09-17 14:14 |
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Peer-Review Started |
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2019-09-17 14:14 |
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To Make the First Decision |
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2019-10-15 00:29 |
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Return for Revision |
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2019-10-15 01:31 |
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Revised |
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2019-10-21 14:41 |
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Second Decision |
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2019-12-13 12:46 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Company Editor-in-Chief |
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2019-12-14 20:07 |
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Articles in Press |
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2019-12-14 20:07 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-02-27 03:25 |
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Publish the Manuscript Online |
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2020-02-28 09:45 |
| ISSN |
2220-3230 (online) |
| Open Access |
This is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Review |
| Article Title |
Post-transplantation lymphoproliferative disorders: Current concepts and future therapeutic approaches
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Fedaey Abbas, Mohsen El Kossi, Ihab Sakr Shaheen, Ajay Sharma and Ahmed Halawa |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ahmed Halawa, FRSC, MD, Associate Professor, Senior Lecturer, Department of Transplantation, Sheffield Teaching Hospitals, Herries Road, Sheffield S5 7AU, United Kingdom. ahmed.halawa@sth.nhs.uk |
| Key Words |
Lymphoproliferative disorders; Epstein-Barr virus; Solid organ transplant; Hematopoietic stem cell transplant; Post-transplant lymphoproliferative disorder prevention; Future therapies |
| Core Tip |
Post-transplant lymphoproliferative disorders (PTLD) is a serious complication related to the intensity of post-transplant immunosuppression. The role of Epstein-Barr virus (EBV) in PTLD evolution is well established; however, development of PTLD in EBV negative patients is not uncommon. The key step in the management of PTLD is to reduce the immunosuppressive load. Transplant clinicians should be vigilant to the possibility of this complication, particularly in patients with past history of exposure to immunosuppression during treatment of the primary renal disease. High index of suspicion is crucial for timely diagnosis. Therapeutic options include rituximab, chemotherapy, antivirals, adoptive therapy and surgery. |
| Publish Date |
2020-02-28 09:45 |
| Citation |
Abbas F, El Kossi M, Shaheen IS, Sharma A, Halawa A. Post-transplantation lymphoproliferative disorders: Current concepts and future therapeutic approaches. World J Transplant 2020; 10(2): 29-46 |
| URL |
https://www.wjgnet.com/2220-3230/full/v10/i2/29.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v10.i2.29 |
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