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Articles Published Processes
12/28/2019 9:29:28 AM | Browse: 986 | Download: 2202
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Received |
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2019-09-29 02:44 |
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Peer-Review Started |
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2019-09-21 07:11 |
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First Decision by Editorial Office Director |
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2019-11-27 04:55 |
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Return for Revision |
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2019-11-27 04:55 |
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Revised |
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2019-12-03 11:02 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2019-12-13 07:53 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2019-12-14 02:42 |
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Articles in Press |
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2019-12-14 02:42 |
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Edit the Manuscript by Language Editor |
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2019-12-20 00:39 |
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Typeset the Manuscript |
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2019-12-27 07:13 |
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Publish the Manuscript Online |
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2019-12-28 09:29 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2019. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
Comprehensive multi-omics analysis identified core molecular processes in esophageal cancer and revealed GNGT2 is a potential prognostic marker
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guo-Min Liu, Tian-Cheng Lu, Li-Wei Duan, Wen-Yuan Jia, Yun Liu, Xuan Ji, Mao-Lei Sun and Yun-Gang Luo |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Yun-Gang Luo, MD, Attending Doctor, Jilin Provincial Medicine Anti-Tumor Engineering Center, The Second Hospital of Jilin University, No. 218, Ziqiang Street, Changchun 130041, Jilin Province, China. luode544101@163.com |
| Key Words |
Esophageal cancer; Molecular pathogenesis; Enrichment analysis; Gene interaction module; Regulatory factors; GNGT2 |
| Core Tip |
Based on the esophageal cancer-associated RNA-seq in The Cancer Genome Atlas, this study studied the differentially expressed genes of esophageal cancer at various stages, constructed a protein-protein interaction network, obtained 14 dysfunctional modules, and screened out Hub genes. We further performed enrichment analysis to predict non-coding RNA and transcription factors, as well as methylation analysis of the genes in the module. A series of regulatory factors we predicted have a certain degree of regulation on the potential dysfunction mechanism of esophageal cancer, which provides a new idea for the subsequent study of esophageal cancer. |
| Publish Date |
2019-12-28 09:29 |
| Citation |
Liu GM, Lu TC, Duan LW, Jia WY, Liu Y, Ji X, Sun ML, Luo YG. Comprehensive multi-omics analysis identified core molecular processes in esophageal cancer and revealed GNGT2 is a potential prognostic marker. World J Gastroenterol 2019; 25(48): 6890-6901 |
| URL |
https://www.wjgnet.com/1007-9327/full/v25/i48/6890.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v25.i48.6890 |
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