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Articles Published Processes
1/16/2020 7:58:40 AM | Browse: 837 | Download: 2002
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Received |
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2019-10-22 16:46 |
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Peer-Review Started |
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2019-10-15 19:11 |
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To Make the First Decision |
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Return for Revision |
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2019-11-27 03:31 |
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Revised |
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2019-12-11 17:37 |
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Second Decision |
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2019-12-19 04:10 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2019-12-22 12:06 |
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Articles in Press |
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2019-12-22 12:06 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-01-14 02:03 |
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Publish the Manuscript Online |
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2020-01-16 07:58 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article which was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020 Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Metabolite profile comparisons between ascending and descending colon tissue in healthy adults
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Bridget A Baxter, Kristopher D Parker, Michael J Nosler, Sangeeta Rao, Rebecca Craig, Catherine Seiler and Elizabeth P Ryan |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| the CancerCure Foundation and the University of Colorado Cancer Center Support Grant, Division of Cancer Control and Prevention (Aurora, CO) |
P30CA046934 |
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| Corresponding Author |
Elizabeth P Ryan, PhD, Associate Professor, Department of Environmental and Radiological Health Sciences, Colorado State University, 1617 Campus Delivery, Fort Collins, CO 80523, United States. e.p.ryan@colostate.edu |
| Key Words |
Colon; Ascending; Descending; Metabolomics; Obesity; Stool |
| Core Tip |
This study identified metabolite profile differences between right-ascending and left-descending colon from normal, overweight or obese adults. We also show that stool metabolite composition does not accurately reflect the right-ascending colon. There is limited knowledge of human colon small molecules and metabolite signatures that may impact colon cancer risk. Colon cancer of the right-ascending colon has a poorer prognosis and reduced survival outcome when compared to colon cancer on the left-descending colon. Diet and lifestyle are additional factors of overweight and obesity that may influence colon tissue metabolite composition with respect to inflammation. Right and left colon metabolite profiles may be helpful to evaluate after interventions that seek to prevent or mitigate cancer risk. |
| Publish Date |
2020-01-16 07:58 |
| Citation |
Baxter BA, Parker KJ, Nosler MJ, Rao S, Craig R, Seiler C, Ryan EP. Metabolite profile comparisons between ascending and descending colon tissue in healthy adults. World J Gastroenterol 2020; 26(3): 335-352 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i3/335.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i3.335 |
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