Publication Name	World Journal of Gastroenterology
Manuscript ID	5185
Country	Greece

Received	2013-08-21 08:02
Peer-Review Started	2013-08-21 16:19
To Make the First Decision	2013-09-09 16:55
Return for Revision	2013-09-15 19:22
Revised	2013-09-23 19:04
Second Decision	2014-01-20 18:32
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-20 19:13
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-14 08:23
Publish the Manuscript Online	2014-02-26 11:18

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Topic Highlights
Article Title	Clock genes: Their role in colorectal cancer
Manuscript Source	Invited Manuscript
All Author List	Theodoros Karantanos, George Theodoropoulos, Dimitrios Pektasides and Maria Gazouli
Funding Agency and Grant Number
Corresponding Author	Maria Gazouli, Assistant Professor, Department of Basic Medical Science, Laboratory of Biology, School of Medicine, University of Athens, Michalakopoulou 176, 11725 Athens, Greece. mgazouli@med.uoa.gr
Key Words	Clock genes; Colorectal cancer; Development; Prognosis
Core Tip	Clock genes are involved in numerous cellular activities such as cell cycle and DNA repair with various implications in the development of colorectal cancer. Multiple clinical and epidemiological data support these correlations and suggest that altered expression of these genes may be critical for the initiation and progression of this disease while their levels may predict bad response to traditional therapeutic approaches and poor clinical outcome. Finally, the defective circadian system may represent an attractive and currently unknown pathway which can be targeted by novel agents in aggressive colorectal cancers.
Publish Date	2014-02-26 11:18
Citation	Karantanos T, Theodoropoulos G, Pektasides D, Gazouli M. Clock genes: Their role in colorectal cancer. World J Gastroenterol 2014; 20(8): 1986-1992
URL	http://www.wjgnet.com/1007-9327/full/v20/i8/1986.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i8.1986

Full Article (PDF)	WJG-20-1986.pdf
Full Article (Word)	WJG-20-1986.doc
Manuscript File	5185-Review.docx
Answering Reviewers	5185-Answering reviewers.pdf
Copyright License Agreement	5185-Copyright assignment.pdf
Peer-review Report	5185-Peer review(s).pdf
Scientific Editor Work List	5185-Scientific editor work list.doc