| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Control Study |
| Article Title |
Changing delta hepatitis patient profile: A single center experience in Valencia region, Spain
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Helena Hernàndez i Èvole, Álvaro Briz Redón and Marina Berenguer |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Marina Berenguer, MD, Professor, Department of digestive diseases, Berenguer, M (reprint author), Hosp La Fe, Liver Transplantat & Hepatol Unit, C Bulevar Sur Sn Torre F-5, Valencia 46026, Spain., La Fe University Hospital, University of Valencia, La Fe University Hospital and Ciberehd, Servicio de Medicina Digestivo (Torre F-5), La Fe University Hospital, Ciberehd*, University of Valencia, Avda Fernando Abril Martorell n 106, Valencia, Spain, Valencia 46026, Spain. marina.berenguer@uv.es |
| Key Words |
Viral hepatitis; Delta hepatitis; Cirrhosis; Liver transplantation; Immigration; Valencia |
| Core Tip |
Our data show that there has been a change in the hepatitis Delta virus-infected patient profile in our unit. Most patients infected in the 80s, due to intravenous drug abuse, have progressed to cirrhosis and/or hepatocellular carcinoma and therefore still represent a significant burden on our Hepatology Unit. However, our main concern is with newly diagnosed patients as there is a clear delay in the diagnosis of infection and cirrhosis. In addition, follow-up in their home countries has been poor. Most of them come from Eastern Europe and a prior medical intervention was the main route of infection. We must also take into account the presence of comorbidities, e.g., metabolic syndrome and alcohol intake; which may contribute to the aggressive progression of the disease. Therefore, we must devote our efforts to control these aspects, as well as, to find some effective treatment, given the poor results offered by pegylated--interferon. |
| Publish Date |
2020-06-28 07:49 |
| Citation |
Hernàndez-Èvole H, Briz-Redón A, Berenguer M. Changing delta hepatitis patient profile: A single center experience in Valencia region, Spain. World J Hepatol 2020; 12(6): 277-287 |
| URL |
https://www.wjgnet.com/1948-5182/full/v12/i6/277.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v12.i6.277 |
