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Articles Published Processes
3/6/2020 8:20:24 AM | Browse: 962 | Download: 1478
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Received |
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2019-11-13 21:55 |
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Peer-Review Started |
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2019-11-13 21:56 |
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To Make the First Decision |
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Return for Revision |
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2020-01-15 19:42 |
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Revised |
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2020-02-10 15:02 |
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Second Decision |
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2020-02-20 10:51 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-02-23 22:48 |
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Articles in Press |
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2020-02-23 22:48 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-03-06 03:26 |
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Publish the Manuscript Online |
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2020-03-06 08:20 |
| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Randomized Controlled Trial |
| Article Title |
Double-blind randomized controlled study of the efficacy, safety and tolerability of eszopiclone vs placebo for the treatment of patients with post-traumatic stress disorder and insomnia
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sheila M Dowd, Alyson K Zalta, Helen J Burgess, Elizabeth C Adkins, Zerbrina Valdespino-Hayden and Mark H Pollack |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Institutes of Mental Health |
5R34MH91338-03 |
| National Institutes of Mental Health |
K23 MH103394 |
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| Corresponding Author |
Sheila M Dowd, PhD, Associate Professor, Department of Psychiatry and Behavioral Sciences, Rush University Medical Center, 1645 West Jackson Blvd Suite 400, Chicago, IL 60601, United States. sheila_dowd@rush.edu |
| Key Words |
Trauma; Sleep disturbance; Hypnotic; Post-traumatic stress disorder; ; |
| Core Tip |
Sleep disturbance is a core feature of post-traumatic stress disorder (PTSD) yet few studies have examined the impact of psychopharmacotherapy. Results from this randomized controlled parallel study in individuals with PTSD and sleep disturbance did not demonstrate a significant relative improvement for eszopiclone (ESZ) vs placebo treated patients. Although patients receiving ESZ did experience significant improvement in measures of PTSD and sleep disturbance, placebo treated patients also significantly improved on these outcomes. Thus the potential role for ESZ in the treatment of PTSD remains uncertain until a larger more definitive trial is undertaken. |
| Publish Date |
2020-03-06 08:20 |
| Citation |
Dowd SM, Zalta AK, Burgess HJ, Adkins EE, Valdespino-Hayden Z, Pollack MH. Double-blind randomized controlled study of the efficacy, safety and tolerability of eszopiclone vs placebo for the treatment of patients with post-traumatic stress disorder and insomnia. World J Psychiatr 2020; 10(3): 21-28 |
| URL |
https://www.wjgnet.com/2220-3206/full/v10/i3/21.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v10.i3.21 |
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