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Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 52958
Country China
Received
2019-12-13 12:13
Peer-Review Started
2019-12-13 12:13
To Make the First Decision
2020-03-11 00:55
Return for Revision
2020-03-11 05:59
Revised
2020-03-11 15:34
Second Decision
2020-03-25 10:45
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-03-26 21:34
Articles in Press
2020-03-26 21:34
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2020-04-14 01:39
Publish the Manuscript Online
2020-04-15 12:00
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Retrospective Study
Article Title Prognostic significance of systemic immune-inflammation index in patients with intrahepatic cholangiocarcinoma undergoing hepatic resection
Manuscript Source Unsolicited Manuscript
All Author List Hui Li, Jin-Ju Wang, Min Zhang, Bo Ren, Jia-Xin Li, Lin Xu and Hong Wu
ORCID
Author(s) ORCID Number
Hui Li http://orcid.org/0000000172872690
Jin-Ju Wang http://orcid.org/0000000312107676
Min Zhang http://orcid.org/0000-0002-6846-2653
Bo Ren http://orcid.org/0000-0002-3160-1971
Jia-Xin Li http://orcid.org/0000-0003-2356-5103
Lin Xu http://orcid.org/0000-0002-1595-5622
Hong Wu http://orcid.org/0000-0001-5397-4800
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 81972747
National Natural Science Foundation of China 81872004
National Natural Science Foundation of China 81800564
National Natural Science Foundation of China 81770615
National Natural Science Foundation of China 81700555
National Natural Science Foundation of China 81672882
Science and Technology Support Program of Sichuan Province 2019YFQ0001
Science and Technology Support Program of Sichuan Province 2018SZ0115
Science and Technology Support Program of Sichuan Province 2017SZ0003
Science and Technology Program of Tibet Autonomous Region XZ201801-GB-02
1.3.5 Project for Disciplines of Excellence, West China Hospital, Sichuan University ZYJC18008
Corresponding Author Hong Wu, MD, PhD, Professor, Surgeon, Department of Liver Surgery and Liver Transplantation, West China Hospital of Sichuan University, No.37 Guoxue Lane, Wuhou District, Chengdu 610041, Sichuan Province, China. wuhong7801@163.com
Key Words Intrahepatic cholangiocarcinoma; Systemic immune-inflammation index; Hepatectomy; Prognostic predictor; Long-term outcomes; Immunotherapy
Core Tip Inflammation has been reported to play a crucial role in tumor biology. Systemic immune-inflammation index (SII), an inflammation-based index, was a composite measure of neutrophil, platelet and lymphocyte counts. No data exists until now, has evaluated its prognostic value for intrahepatc cholangiocarcinoma (ICC). This study aimed to investigate the clinical significance of preoperative SII levels in ICC patients undergoing curative resection. Patients with increased SII level were associated with worse overall survival and earlier tumor recurrence. In the future, the SII could help stratifying patients with ICC, thus guiding therapeutic choices, especially in immunotherapy.
Publish Date 2020-04-15 12:00
Citation Li H, Wang JJ, Zhang M, Ren B, Li JX, Xu L, Wu H. Prognostic significance of systemic immune-inflammation index in patients with intrahepatic cholangiocarcinoma undergoing hepatic resection. World J Gastrointest Oncol 2020; 12(4): 467-482
URL https://www.wjgnet.com/1948-5204/full/v12/i4/467.htm
DOI https://dx.doi.org/10.4251/wjgo.v12.i4.467
Full Article (PDF) WJGO-12-467.pdf
Full Article (Word) WJGO-12-467.docx
Manuscript File 52958-Review.docx
Answering Reviewers 52958-Answering reviewers.pdf
Audio Core Tip 52958-Audio core tip.m4a
Conflict-of-Interest Disclosure Form 52958-Conflict-of-interest statement.pdf
Copyright License Agreement 52958-Copyright license agreement.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 52958-Grant application form(s).pdf
Signed Informed Consent Form(s) or Document(s) 52958-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 52958-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 52958-Language certificate.pdf
Supplementary Material 52958-Supplementary material.pdf
Peer-review Report 52958-Peer-review(s).pdf
Scientific Misconduct Check 52958-Scientific misconduct check.pdf
Scientific Editor Work List 52958-Scientific editor work list.pdf