| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Otorhinolaryngology |
| Manuscript Type |
Case Control Study |
| Article Title |
Removal of biofilm is essential for long-term ventilation tube retention
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Qiang Ma, Hui Wang, Zheng-Nong Chen, Ya-Qin Wu, Dong-Zhen Yu, Peng-Jun Wang, Hai-Bo Shi and Kai-Ming Su |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Shanghai Leadership Talent Training Plan |
2017062 |
| the Key Project of Shanghai Jiao Tong University Medicine Science and Engineering Interdisciplinary Foundation |
YG2016ZD02 |
| Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support |
20152233 |
| Multi-Center Clinical Research Plan of Medical College of Shanghai Jiao Tong University |
DLY201823 |
| Clinical Research Plan of Shanghai Shen Kang Hospital Development Center |
16CR4022A |
| Clinical Research Plan of Shanghai Shen Kang Hospital Development Center |
16CR3041A |
| National Natural Science Foundation of China |
81570910 |
|
| Corresponding Author |
Peng-Jun Wang, MD, Doctor, Department of Otorhinolaryngology-Head & Neck Surgery, the Sixth People's Hospital affiliated to Shanghai Jiaotong University, 600 Yishan Road, Shanghai 200233, China. wangpj@sjtu.edu.cn |
| Key Words |
Tympanostomy tubes; Biofilm; Complication management; Long-term retention; Ménière disease; Refractory otitis media with effusion |
| Core Tip |
Long-term ventilation tube retention is necessary in many diseases, such as refractory otitis media with effusion and eustachian tube dysfunction, as well as with the use of Meniett therapy for Ménière disease. However, conventional ventilation tubes are expelled spontaneously within 3 to 12 mo because of tube extrusion or obstruction. Therefore, patients have to undergo two or more myringotomy with ventilation tube placement procedures, along with the risks of anesthesia and surgery, excessive injury to the tympanic membrane and external auditory canal, medical care costs, and impact on school or work. The biofilm plays a crucial role in the development of extrusion or obstruction after myringotomy with ventilation tube placement. It was revealed that, despite the use of short-term tube, biofilm removal has been proven to be a safe and effective treatment for long-term tube retention. |
| Publish Date |
2020-04-30 15:27 |
| Citation |
Ma Q, Wang H, Chen ZN, Wu YQ, Yu DZ, Wang PJ, Shi HB, Su KM. Removal of biofilm is essential for long-term ventilation tube retention. World J Clin Cases 2020; 8(9): 1592-1599 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i9/1592.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i9.1592 |
