Publication Name	World Journal of Gastroenterology
Manuscript ID	5336
Country	Canada

Received	2013-08-30 10:41
Peer-Review Started	2013-08-30 17:58
To Make the First Decision	2013-12-16 17:57
Return for Revision	2013-09-29 10:22
Revised	2013-10-22 10:15
Second Decision	2014-01-08 18:19
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2014-01-08 18:33
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-02-27 12:01
Publish the Manuscript Online	2014-03-12 14:46

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Meta-Analysis
Article Title	Antiviral therapy in cytomegalovirus-positive ulcerative colitis: A systematic review and meta-analysis
Manuscript Source	Invited Manuscript
All Author List	Uri Kopylov, Noa Eliakim-Raz, Andrew Szilagy, Ernest Seidman, Shomron Ben-Horin and Lior Katz
Funding Agency and Grant Number
Corresponding Author	Dr. Uri Kopylov, Division of Gastroenterology, McGill University Health Center, Montreal, 1650 Cedar Avenue, Quebec H3G 1A4, Canada. ukopylov@gmail.com
Key Words	Ulcerative colitis; Cytomegalovirus; Colectomy; Antiviral treatment; Gancyclovir; Foscarnet
Core Tip	We have undertaken a meta-analysis of the existing literature in order to evaluate the impact of antiviral therapy on the outcome (colectomy rate) of ulcerative colitis patients with documented presence of cytomegalovirus. Nine studies of low to moderate quality with significant heterogeneity were included. Patients treated with antivirals did not have a better outcome in comparison to those who were not. These results should be interpreted with caution in view of low quality of the included studies and several potential biases. Additional high-quality studies are required to define the optimal diagnostic and therapeutic strategy for these patients
Publish Date	2014-03-12 14:46
Citation	Kopylov U, Eliakim-Raz N, Szilagy A, Seidman E, Ben-Horin S, Katz L. Antiviral therapy in cytomegalovirus-positive ulcerative colitis: A systematic review and meta-analysis. World J Gastroenterol 2014; 20(10): 2695-2703
URL	http://www.wjgnet.com/1007-9327/full/v20/i10/2695.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i10.2695

Full Article (PDF)	WJG-20-2695.pdf
Full Article (Word)	WJG-20-2695.doc
Manuscript File	5336-Review.docx
Answering Reviewers	5336-Answering reviewers.pdf
Copyright License Agreement	5336-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5336-Language certificate.pdf
Peer-review Report	5336-Peer review(s).pdf
Scientific Editor Work List	5336-Scientific editor work list.doc