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Articles Published Processes
6/14/2020 1:45:26 PM | Browse: 877 | Download: 1678
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Received |
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2019-12-28 07:52 |
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Peer-Review Started |
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2019-12-19 10:26 |
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To Make the First Decision |
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Return for Revision |
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2020-01-19 00:43 |
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Revised |
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2020-05-14 08:10 |
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Second Decision |
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2020-05-27 05:56 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-28 03:05 |
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Articles in Press |
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2020-05-28 03:05 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-06-11 01:33 |
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Publish the Manuscript Online |
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2020-06-14 13:45 |
| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Basic Study |
| Article Title |
High plasma levels of COL10A1 are associated with advanced tumor stage in gastric cancer patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Laura Necula, Lilia Matei, Denisa L Dragu, Ioana Pitica, Ana I Neagu, Coralia Bleotu, Simona Dima, Irinel Popescu, Carmen C Diaconu and Mihaela Chivu-Economescu |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Romanian National Authority for Scientific Research and Innovation, CNCS - UEFISCDI |
PN-III-P4-ID-PCCF2016-0158 |
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| Corresponding Author |
Mihaela Chivu-Economescu, PhD, Research Assistant Professor, Research Scientist, Senior Researcher, Department of Cellular and Molecular Pathology, Stefan S. Nicolau Institute of Virology, 285 Mihai Bravu Ave, Bucharest 030304, Romania. mihaela.economescu@virology.ro |
| Key Words |
Gastric cancer; COL10A1; Circulating biomarkers; Early diagnosis; Poor prognosis; Tumor stage |
| Core Tip |
Gastric cancer remains an aggressive malignancy with a high rate of mortality, characterized by limited effective treatment options and the lack of consistent biomarkers for the diagnosis and prognosis of the patients. The aim of this study was to evaluate the potential of COL10A1 as a circulating biomarker for the diagnosis and prognosis of gastric adenocarcinoma patients. Our results suggest that COL10A1 could be considered a good biomarker for prognosis and also for early detection, as its elevated expression occurred early and remained elevated during cancer progression. |
| Publish Date |
2020-06-14 13:45 |
| Citation |
Necula L, Matei L, Dragu D, Pitica I, Neagu AI, Bleotu C, Dima S, Popescu I, Diaconu CC, Chivu-Economescu M. High plasma levels of COL10A1 are associated with advanced tumor stage in gastric cancer patients. World J Gastroenterol 2020; 26(22): 3024-3033 |
| URL |
https://www.wjgnet.com/1007-9327/full/v26/i22/3024.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v26.i22.3024 |
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