| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Observational Study |
| Article Title |
Comparison of four non-alcoholic fatty liver disease detection scores in a Caucasian population
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lars Lind, Lars Johansson, Håkan Ahlström, Jan W Eriksson, Anders Larsson, Ulf Risérus, Joel Kullberg and Jan Oscarsson |
| ORCID |
|
| Funding Agency and Grant Number |
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| Corresponding Author |
Lars Lind, MD, PhD, Professor, Department of Medical Sciences, Uppsala University, Akademiska sjukhuset, Entrance 40, 5th floor, Uppsala 75185, Sweden. lars.lind@medsci.uu.se |
| Key Words |
Comparison; EFFECT studies; Fatty liver; Non-alcoholic fatty liver disease; Non-invasive indices; Screening |
| Core Tip |
Several non-invasive indices based on routinely available biochemical and physical parameters have been developed for the detection of non-alcoholic fatty liver (NAFLD) disease. However, data comparing the efficacy of these indices within a population-based sample are lacking. Here we compared four non-invasive indices, namely, fatty liver index, lipid accumulation product, hepatic steatosis index, and liver fat score, in a population-based (Prospective investigation of obesity, energy and metabolism study) sample and a high-risk (EFFECT studies) sample. Our study demonstrated differences in NAFLD detection between the scores in the two samples. Of the four evaluated scores, fatty liver index was preferable in the population-based sample (NAFLD prevalence, 23%), whereas liver fat score performed best in the high-risk sample (NAFLD prevalence, 73%). |
| Publish Date |
2020-04-23 10:34 |
| Citation |
Lind L, Johansson L, Ahlström H, Eriksson JW, Larsson A, Risérus U, Kullberg J, Oscarsson J. Comparison of four non-alcoholic fatty liver disease detection scores in a Caucasian population. World J Hepatol 2020; 12(4): 149-159 |
| URL |
https://www.wjgnet.com/1948-5182/full/v12/i4/149.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v12.i4.149 |
