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Publication Name World Journal of Gastroenterology
Manuscript ID 5345
Country Japan
Received
2013-08-31 19:06
Peer-Review Started
2013-09-02 16:52
To Make the First Decision
2013-09-27 16:58
Return for Revision
2013-09-29 10:23
Revised
2013-10-30 21:15
Second Decision
2013-12-05 19:23
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2013-12-06 11:56
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2014-01-08 19:50
Publish the Manuscript Online
2014-01-26 20:08
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Intra-gastric triacetin alters upper gastrointestinal motility in conscious dogs
Manuscript Source Invited Manuscript
All Author List Kazumasa Oosaka, Masaaki Tokuda and Naohiro Furukawa
Funding Agency and Grant Number
Corresponding Author Dr. Kazumasa Oosaka, Research and Development Department, Fushimi Pharmaceutical Co., Ltd., Nakatsu-cho 1676, Marugame, Kagawa 7638605, Japan. ohsaka@fushimi.co.jp
Key Words Gastrointestinal motility; Barostat; Proximal gastric relaxation; Short-chain triglycerides
Core Tip Intra-gastric infusion of short-chain triglycerides, such as triacetin, has been shown to delay gastric emptying in conscious dogs, but the influence on upper gastrointestinal motility is unknown. The current study examined time-dependent changes in motility following intra-gastric triacetin administration at various doses in conscious dogs and evaluated the effects of a fasted vs fed state. Compared to infusion of water (vehicle) alone, the 1.0% and 2.0% triacetin doses induced a significant increase in the proximal stomach receptive volume, a temporary inhibition of gastric antral contractions, and an increase in the duodenal contractions in fasted dogs.
Publish Date 2014-01-26 20:08
Citation Oosaka K, Tokuda M, Furukawa N. Intra-gastric triacetin alters upper gastrointestinal motility in conscious dogs. World J Gastroenterol 2014; 20(4): 1054-1060
URL http://www.wjgnet.com/1007-9327/full/v20/i4/1054.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i4.1054
Full Article (PDF) WJG-20-1054.pdf
Full Article (Word) WJG-20-1054.doc
Manuscript File 5345-Review.docx
Answering Reviewers 5345-Answering reviewers.pdf
Biostatistics Review Certificate Biostatistician_Review_Report_20130831042823.pdf
Copyright License Agreement 5345-Copyright assignment.pdf
Institutional Review Board Approval Form or Document Ethics_Committee_20130831042709.pdf
Non-Native Speakers of English Editing Certificate 5345-Language certificate.pdf
Peer-review Report 5345-Peer review(s).pdf
Scientific Editor Work List 5345-Scientific editor work list.doc