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Articles Published Processes
4/7/2020 9:33:59 AM | Browse: 912 | Download: 1593
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Received |
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2019-12-23 14:38 |
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Peer-Review Started |
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2019-12-23 14:39 |
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To Make the First Decision |
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2020-02-26 11:18 |
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Return for Revision |
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2020-02-27 11:17 |
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Revised |
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2020-03-18 12:03 |
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Second Decision |
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2020-03-30 12:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-31 19:11 |
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Articles in Press |
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2020-03-31 19:11 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-04-07 06:15 |
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Publish the Manuscript Online |
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2020-04-07 09:33 |
| ISSN |
1949-8454 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Microbiology |
| Manuscript Type |
Review |
| Article Title |
Why the discovery of adherent-invasive Escherichia coli molecular markers is so challenging?
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Carla Camprubí-Font and Margarita Martinez-Medina |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Spanish Ministry of Economy and Competitiveness |
SAF2017-82261-P |
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| Corresponding Author |
Margarita Martinez-Medina, PhD, Associate Professor, Laboratory of Molecular Microbiology, Department of Biology, Universitat de Girona, C/Maria Aurèlia Capmany, 40, Girona 17003, Spain. marga.martinez@udg.edu |
| Key Words |
Crohn’s disease; Adherent-invasive Escherichia coli; Molecular markers; Genetics; Inflammatory bowel disease; Signature sequences |
| Core Tip |
In this review, we thoroughly review the approaches for deciphering adherent-invasive Escherichia coli (AIEC) genetics. The characteristics of putative AIEC molecular markers that could assist in AIEC identification are described. We then discuss several aspects that could explain the difficulty behind the discovery of suitable biomarkers and highlight the importance of standardizing AIEC protocols in order to increase the probability of finding these biomarkers. Finally, we point out new approaches for looking for signature sequences that need to take into account the AIEC phylogenetic origin and strain virulence under particular experimental conditions. |
| Publish Date |
2020-04-07 09:33 |
| Citation |
Camprubí-Font C, Martinez-Medina M. Why the discovery of adherent-invasive Escherichia coli molecular markers is so challenging? World J Biol Chem 2020; In press |
| URL |
https://www.wjgnet.com/1949-8454/full/v11/i1/1.htm |
| DOI |
https://dx.doi.org/10.4331/wjbc.v11.i1.1 |
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