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6/24/2020 10:31:56 AM | Browse: 593 | Download: 1223
Publication Name World Journal of Clinical Oncology
Manuscript ID 53578
Country Italy
Received
2019-12-25 20:15
Peer-Review Started
2019-12-24 21:29
To Make the First Decision
Return for Revision
2020-04-07 23:33
Revised
2020-04-13 16:07
Second Decision
2020-05-12 08:24
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2020-05-13 06:40
Articles in Press
2020-05-13 06:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
2020-05-26 08:02
Typeset the Manuscript
2020-06-23 08:57
Publish the Manuscript Online
2020-06-24 10:31
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright © The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Immunology
Manuscript Type Observational Study
Article Title Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study
Manuscript Source Invited Manuscript
All Author List Giammaria Fiorentini, Donatella Sarti, Alberto Patriti, Emilio Eugeni, Francesco Guerra, Francesco Masedu, Andrew Ray Mackay and Stefano Guadagni
ORCID
Author(s) ORCID Number
Giammaria Fiorentini http://orcid.org/0000-0002-5615-889X
Donatella Sarti http://orcid.org/0000-0002-8031-7846
Alberto Patriti http://orcid.org/0000-0003-2414-268X
Emilio Eugeni http://orcid.org/0000-0001-7989-6660
Francesco Guerra http://orcid.org/0000-0003-2891-4659
Francesco Masedu http://orcid.org/0000-0003-0290-5324
Andrew Ray Mackay http://orcid.org/0000-0001-7096-3759
Stefano Guadagni http://orcid.org/0000-0001-8525-084X
Funding Agency and Grant Number
Corresponding Author Giammaria Fiorentini, MD, Adjunct Professor, Chief Doctor, Director, Department of Onco-Hematology, Azienda Ospedaliera “Ospedali Riuniti Marche Nord”, via Lombroso 1, Pesaro 61122, Italy. g.fiorentini@alice.it
Key Words Immune response; Hyperthermic intraperitoneal chemotherapy; Peritoneal metastases; Regulatory T lymphocytes; Pseudomixoma peritonei; Colorectal cancer
Core Tip Reports indicate that thermal tumor ablation has potential immunomodulatory activity, illustrated by the intense inflammatory cell response that associates with this procedure, characterized by thermally ablated tissue transitional zone infiltration by immunological and inflammatory cell populations, including: dendritic cells, neutrophils, macrophages, B and T lymphocytes and natural killer cells. In the present study, we evaluated and confirm that hyperthermic intraperitoneal chemotherapy for peritoneal metastases also exhibits immunomodulatory activity, inducing the general activation of an adaptive immune response.
Publish Date 2020-06-24 10:31
Citation Fiorentini G, Sarti D, Patriti A, Eugeni E, Guerra F, Masedu F, Mackay AR, Guadagni S. Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study. World J Clin Oncol 2020; 11(6): 397-404
URL https://www.wjgnet.com/2218-4333/full/v11/i6/397.htm
DOI https://dx.doi.org/10.5306/wjco.v11.i6.397
Full Article (PDF) WJCO-11-397.pdf
Full Article (Word) WJCO-11-397.docx
STROBE Statement 53578-STROBE-Statement-revision.pdf
Manuscript File 53578-Review-Webster J.docx
Answering Reviewers 53578-Answering reviewers.pdf
Audio Core Tip 53578-Audio core tip.m4a
Biostatistics Review Certificate 53578-Biostatistics statement.pdf
Conflict-of-Interest Disclosure Form 53578-Conflict-of-interest statement.pdf
Copyright License Agreement 53578-Copyright license agreement.pdf
Signed Informed Consent Form(s) or Document(s) 53578-Informed consent statement.pdf
Institutional Review Board Approval Form or Document 53578-Institutional review board statement.pdf
Non-Native Speakers of English Editing Certificate 53578-Language certificate.pdf
Peer-review Report 53578-Peer-review(s).pdf
Scientific Misconduct Check 53578-CrossCheck.png
Scientific Misconduct Check 53578-Bing-Zhang L-2.png
Scientific Misconduct Check 53578-Scientific misconduct check.pdf
Scientific Editor Work List 53578-Scientific editor work list.pdf