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Articles Published Processes
6/24/2020 10:31:56 AM | Browse: 729 | Download: 1772
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Received |
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2019-12-25 20:15 |
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Peer-Review Started |
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2019-12-24 21:29 |
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To Make the First Decision |
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Return for Revision |
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2020-04-07 23:33 |
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Revised |
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2020-04-13 16:07 |
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Second Decision |
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2020-05-12 08:24 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-05-13 06:40 |
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Articles in Press |
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2020-05-13 06:40 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-05-26 08:02 |
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Typeset the Manuscript |
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2020-06-23 08:57 |
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Publish the Manuscript Online |
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2020-06-24 10:31 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Immunology |
Manuscript Type |
Observational Study |
Article Title |
Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study
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Manuscript Source |
Invited Manuscript |
All Author List |
Giammaria Fiorentini, Donatella Sarti, Alberto Patriti, Emilio Eugeni, Francesco Guerra, Francesco Masedu, Andrew Ray Mackay and Stefano Guadagni |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Giammaria Fiorentini, MD, Adjunct Professor, Chief Doctor, Director, Director, Department of Onco-Hematology, Azienda Ospedaliera “Ospedali Riuniti Marche Nord”, via Lombroso 1, Pesaro 61122, Italy. g.fiorentini@alice.it |
Key Words |
Immune response; Hyperthermic intraperitoneal chemotherapy; Peritoneal metastases; Regulatory T lymphocytes; Pseudomixoma peritonei; Colorectal cancer |
Core Tip |
Reports indicate that thermal tumor ablation has potential immunomodulatory activity, illustrated by the intense inflammatory cell response that associates with this procedure, characterized by thermally ablated tissue transitional zone infiltration by immunological and inflammatory cell populations, including: dendritic cells, neutrophils, macrophages, B and T lymphocytes and natural killer cells. In the present study, we evaluated and confirm that hyperthermic intraperitoneal chemotherapy for peritoneal metastases also exhibits immunomodulatory activity, inducing the general activation of an adaptive immune response. |
Publish Date |
2020-06-24 10:31 |
Citation |
Fiorentini G, Sarti D, Patriti A, Eugeni E, Guerra F, Masedu F, Mackay AR, Guadagni S. Immune response activation following hyperthermic intraperitoneal chemotherapy for peritoneal metastases: A pilot study. World J Clin Oncol 2020; 11(6): 397-404 |
URL |
https://www.wjgnet.com/2218-4333/full/v11/i6/397.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v11.i6.397 |
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