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8/29/2014 11:31:00 AM | Browse: 822 | Download: 824
Publication Name World Journal of Gastroenterology
Manuscript ID 5364
Country/Territory China
Received
2013-09-03 10:02
Peer-Review Started
2013-09-03 14:20
To Make the First Decision
2013-10-29 12:36
Return for Revision
2013-10-30 10:51
Revised
Second Decision
2014-01-08 18:20
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief
2014-01-08 18:32
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
2014-02-28 20:37
Typeset the Manuscript
2014-03-28 14:15
Publish the Manuscript Online
2014-04-17 13:27
ISSN 1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Autobiography
Article Title Death decoy receptor overexpression and increased malignancy risk in colorectal cancer
Manuscript Source Invited Manuscript
All Author List Liang Zong, Ping Chen and Da-Xin Wang
Funding Agency and Grant Number
Corresponding Author Liang Zong, MD, PhD, Department of Gastrointestinal Surgery, Su Bei People’s Hospital of Jiangsu Province, Yangzhou University, No. 98 Nantong West Road, Yangzhou 225001, Jiangsu Province, China. 250537471@qq.com
Key Words Colorectal carcinoma; Human epidermal growth factor receptor 2; Death decoy receptor; Immunohistochemistry; Prognosis
Core Tip Overexpression of the human epidermal growth factor receptor 2 (HER2) and death decoy receptor (DcR3) has been observed in clinical specimens of colorectal cancer, but their roles in prognosis remain unknown. In this systematic investigation of the immunohistochemistry staining patterns of HER2 and DcR3 in 300 clinical specimens, only DcR3 overexpression was identified as a potential prognostic marker of colorectal cancer. Specifically, DcR3 tumor-positive staining showed a strong statistical correlation with lymph node metastasis and poor overall survival. Moreover, HER2-positive patients with DcR3 overexpression had poorer overall survival than their DcR3-negative counterparts.
Publish Date 2014-04-17 13:27
Citation Zong L, Chen P, Wang DX. Death decoy receptor overexpression and increased malignancy risk in colorectal cancer. World J Gastroenterol 2014; 20(15): 4440-4445
URL http://www.wjgnet.com/1007-9327/full/v20/i15/4440.htm
DOI http://dx.doi.org/10.3748/wjg.v20.i15.4440
Full Article (PDF) WJG-20-4440.pdf
Full Article (Word) WJG-20-4440.doc
Manuscript File 5364-Review.docx
Answering Reviewers 5364-Answering reviewers.pdf
Copyright License Agreement 5364-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate 5364-Language certificate.pdf
Peer-review Report 5364-Peer review(s).pdf
Scientific Editor Work List 5364-Scientific editor work list.doc