Publication Name	World Journal of Hepatology
Manuscript ID	5374
Country	Italy

Received	2013-09-03 10:31
Peer-Review Started	2013-09-03 14:57
To Make the First Decision	2013-09-17 09:30
Return for Revision	2013-09-17 21:23
Revised	2013-09-26 22:32
Second Decision	2013-11-15 18:59
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-16 01:05
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2013-12-25 08:43
Publish the Manuscript Online	2014-01-11 22:00

ISSN	1948-5182 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Clinical course and prognostic factors of hepatorenal syndrome: A retrospective single-center cohort study
Manuscript Source	Invited Manuscript
All Author List	Anna Licata, Marcello Maida, Ambra Bonaccorso, Fabio Salvatore Macaluso, Maria Cappello, Antonio Craxì and Piero Luigi Almasio
Funding Agency and Grant Number
Corresponding Author	Piero Luigi Almasio, MD, Section of Gastroenterology, Dipartimento Biomedico di Medicina Interna e Specialistica, University of Palermo, Piazza delle Cliniche, 290127 Palermo, Italy. piero.almasio@unipa.it
Key Words	Hepatorenal syndrome; Liver cirrhosis; Hepatitis C virus; Vasoactive drugs; Mortality
Core Tip	Hepatorenal syndrome (HRS) is a life-threatening complication of advanced liver disease. The aims of this study were to investigate the clinical and biochemical features of HRS, to assess short- and long-term survival, and to evaluate the presence of potential predictors of early mortality. Thirty-three patients with liver cirrhosis and HRS were retrospectively reviewed. Median survival was 30 d. By univariate analysis Child-Pugh class C, hepatocellular carcinoma, low serum sodium, high bilirubin and high Model for End-stage Liver Disease (MELD) score were predictive factors of 30-d mortality. By multivariate analysis, only serum sodium < 132 mEq/L and MELD score > 27 were independently associated with survival of less than one month.
Publish Date	2014-01-11 22:00
Citation	Licata A, Maida M, Bonaccorso A, Macaluso FS, Cappello M, Craxì A, Almasio PL. clinical course and prognostic factors of hepatorenal syndrome: a retrospective single-center cohort study. World J Hepatol 2013; 5(12): 685-691
URL	http://www.wjgnet.com/1948-5182/full/v5/i12/685.htm
DOI	http://dx.doi.org/10.4254/wjh.v5.i12.685

Full Article (PDF)	WJH-5-685.pdf
Full Article (Word)	WJH-5-685.doc
Manuscript File	5374-Review.docx
Answering Reviewers	5374-Answering reviewers.pdf
Copyright License Agreement	5374-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	5374-Language certificate.pdf
Peer-review Report	5374-Peer review(s).pdf
Scientific Editor Work List	5374-Scientific editor work list.doc