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Articles Published Processes
9/12/2014 8:41:00 PM | Browse: 1013 | Download: 834
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Received |
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2013-09-03 10:41 |
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Peer-Review Started |
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2013-09-03 15:00 |
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To Make the First Decision |
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2013-09-27 16:55 |
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Return for Revision |
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2013-09-29 10:28 |
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Revised |
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2013-10-02 08:00 |
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Second Decision |
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2013-10-14 09:55 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2013-10-14 13:23 |
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Articles in Press |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2013-10-22 16:37 |
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Typeset the Manuscript |
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2013-10-31 09:55 |
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Publish the Manuscript Online |
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2013-11-16 18:29 |
Category |
Gastroenterology & Hepatology |
Manuscript Type |
Topic Highlights |
Article Title |
Transmission of hepatitis C virus: Self-limiting hepatitis or chronic hepatitis?
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Manuscript Source |
Invited Manuscript |
All Author List |
Takafumi Saito and Yoshiyuki Ueno |
Funding Agency and Grant Number |
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Corresponding Author |
Takafumi Saito, MD, Associate Professor, Department of Gastroenterology, Yamagata University School of Medicine, Iida-nishi 2-2-2, Yamagata 990-9585, Japan. tasaitoh@med.id.yamagata-u.ac.jp
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Key Words |
Hepatitis C; Spontaneous clearance; Interleukin 28B; Single nucleotide polymorphism; Interferon-λ |
Core Tip |
Most individuals with hepatitis C virus (HCV) infection develop chronic hepatitis, but in some the hepatitis is resolved in a self-limiting manner in the acute phase of infection. What factors are responsible for this difference in the outcome of hepatitis C? The evolutionary dynamics of the infecting virus and host genetic polymorphisms pertaining mainly to the immune system, including the Interleukin 28B gene, as well as susceptibility to HCV infection, are important in determining the outcome of infection. |
Publish Date |
2013-11-16 18:29 |
Citation |
Saito T, Ueno Y. Transmission of hepatitis C virus: Self-limiting hepatitis or chronic hepatitis? World J Gastroenterol 2013; 19(41): 6957-6961 |
URL |
http://www.wjgnet.com/1007-9327/full/v19/i41/6957.htm |
DOI |
http://dx.doi.org/10.3748/wjg.v19.i41.6957 |
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