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Articles Published Processes
3/26/2020 3:19:09 AM | Browse: 1080 | Download: 1860
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Received |
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2019-12-30 17:10 |
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Peer-Review Started |
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2019-12-30 17:15 |
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To Make the First Decision |
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2020-02-04 09:21 |
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Return for Revision |
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2020-02-11 00:43 |
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Revised |
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2020-02-14 18:02 |
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Second Decision |
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2020-03-04 10:01 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-03-05 06:42 |
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Articles in Press |
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2020-03-05 06:42 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2020-03-17 02:03 |
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Publish the Manuscript Online |
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2020-03-26 03:19 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Medicine, Research & Experimental |
Manuscript Type |
Review |
Article Title |
Microbiota-gut-brain axis and its affect inflammatory bowel disease: Pathophysiological concepts and insights for clinicians
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Manuscript Source |
Invited Manuscript |
All Author List |
Emanuele Sinagra, Erika Utzeri, Gaetano Cristian Morreale, Carlo Fabbri, Fabio Pace and Andrea Anderloni |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Emanuele Sinagra, MD, PhD, Doctor, Doctor, Gastroenterology and Endoscopy Unit, Fondazione Istituto Giuseppe Giglio, Contrada Pietra Pollastra Pisciotto, Cefalù 90015, Italy. emanuelesinagra83@googlemail.com |
Key Words |
Irritable bowel syndrome; Inflammatory bowel disease; Gut-brain axis; Therapy; ; |
Core Tip |
The complex interplay between gut microbiota and the brain, and vice versa, has recently become not only the focus of neuroscience, but also the start point for research regarding many diseases such as inflammatory bowel diseases (IBD) and irritable bowel syndrome. The bi-directional interaction between gut microbiota and the brain is not completely understood. Nonetheless, there is increasing evidence arising from animal and human studies that show how this intricate relationship may contribute to the pathogenesis of IBD, with consequent important implications for the possibility to improve the clinical outcomes of the diseases themselves by acting on the different components of this axis. With the emergence of precision medicine, strategies in which patients with IBD might be categorized other than for standard gut symptom complexes could offer the opportunity to tailor therapies to individual patients. |
Publish Date |
2020-03-26 03:19 |
Citation |
Sinagra E, Utzeri E, Morreale GC, Fabbri C, Pace F, Anderloni A. Microbiota-gut-brain axis and its affect inflammatory bowel disease: Pathophysiological concepts and insights for clinicians. World J Clin Cases 2020; 8(6): 1013-1025 |
URL |
https://www.wjgnet.com/2307-8960/full/v8/i6/1013.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v8.i6.1013 |
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