| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Human epidermal growth factor receptor 2 positive rates in invasive lobular breast carcinoma: The Singapore experience
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Ga-Jing Kee, Ryan Ying-Cong Tan, Sultana Rehena, Joycelyn Jie-Xin Lee, Ma Wai-Wai Zaw, Wei-Xiang Lian, Joe Yeong, Su-Ming Tan, Swee-Ho Lim, Benita Kiat-Tee Tan, Yoon-Sim Yap, Rebecca Alexandra Dent, Fuh-Yong Wong and Guek-Eng Lee |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Ryan Ying-Cong Tan, MBBS, MRCP, Attending Doctor, Division of Medical Oncology, National Cancer Centre, 11 Hospital Drive, Singapore 169610, Singapore. ryan.shea.tan.y.c@singhealth.com.sg |
| Key Words |
Lobular breast cancer; Invasive breast cancer; Human epidermal growth factor receptor 2 positive; Singapore; Clinicopathological characteristics; Prognostic value |
| Core Tip |
We conducted a retrospective review of 864 patients with invasive lobular breast carcinoma (ILC) and examined the clinicopathological characteristics and survival in relation to human epidermal growth factor receptor 2 (HER2) status. Interestingly, our cohort reports a higher prevalence of HER2 positive ILC (10.1%) as compared to some previous studies. HER2 positive ILC was more likely to have poorer prognostic features such as estrogen receptor negative, progesterone receptor negative and higher tumour grade, and these patients have a poorer survival compared to those with HER2 negative ILC. |
| Publish Date |
2020-05-24 11:59 |
| Citation |
Kee GJ, Tan RYC, Rehena S, Lee JJX, Zaw MWW, Lian WX, Yeong J, Tan SM, Lim SH, Tan BKT, Yap YS, Dent RA, Wong FY, Lee GE. Human epidermal growth factor receptor 2 positive rates in invasive lobular breast carcinoma: The Singapore experience. World J Clin Oncol 2020; 11(5): 293-293 |
| URL |
https://www.wjgnet.com/2218-4333/full/v11/i5/292.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v11.i5.283 |
