Publication Name	World Journal of Methodology
Manuscript ID	5388
Country	Belgium

Received	2013-09-04 16:45
Peer-Review Started	2013-09-05 09:03
To Make the First Decision	2013-09-29 10:33
Return for Revision	2013-09-29 18:23
Revised
Second Decision	2013-10-18 10:38
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2013-10-18 11:58
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2013-10-27 20:20
Typeset the Manuscript	2013-11-26 14:43
Publish the Manuscript Online	2014-01-14 13:48

ISSN	2222-0682 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Medicine, Research & Experimental
Manuscript Type	Minireviews
Article Title	Overview of translational (radio)pharmaceutical research related to certain oncological and non-oncological applications
Manuscript Source	Invited Manuscript
All Author List	Marlein Miranda Cona, Peter de Witte, Alfons Verbruggen and Yicheng Ni
Funding Agency and Grant Number	Funding Agency Grant Number KU Leuven Molecular Small Animal Imaging Center MoSAIC KUL EF/05/08 KU Leuven project IOF-HB/08/009 KU Leuven project IOF-HB/12/018 European Union (Asia-Link CfP 2006-EuropeAid/123738/C/ACT/Multi-Proposal) 128-498/111 National Natural Science Foundation of China 81071828 Jiangsu Provincial Natural Science Foundation BK2010594
Corresponding Author	Yicheng Ni, MD, Professor of Medicine, PhD, Chief of Theragnostic Lab, Radiology Section, Department of Imaging and Pathology, University Hospitals, KU Leuven, Herestraat 49, B-3000 Leuven, Belgium. yicheng.ni@med.kuleuven.be
Key Words	Translational medical research; Cancer treatment; OncoCiDia; Vascular disrupting agent; Hypericin; Myocardial infarction; Gallstone; Transflux
Core Tip	Translational medicine converts scientific discovery into clinical applications. Radiopharmacy has played a multidisciplinary role. Based on unique necrosis avidity, OncoCiDia presents a generic approach for management of cancers, on which recent results on its optimization are summarized. Myocardial infarction is a clinical problem. A comparative study between infarct avid iodine-131 labeled-hypericin and commercial 99mTc-Sestamibi is presented. Cholelithiasis may cause biliary complications. The usefulness of Hyp as an optical imaging agent for cholelithiasis is demonstrated. Multiple uses of automatic contrast injectors may reduce costs but can cause cross-contaminations. We developed a radioactive method for safety evaluation of a new replaceable patient-delivery system.
Publish Date	2014-01-14 13:48
Citation	Miranda Cona M, de Witte P, Verbruggen A, Ni Y. An overview of translational (radio)pharmaceutical research related to certain oncological and non-oncological applications. World J Methodol 2013; 3(4): 45-64
URL	http://www.wjgnet.com/2222-0682/full/v3/i4/45.htm
DOI	http://dx.doi.org/10.4329/wjm.v3.i4.45

Manuscript File	5388-Review.docx
Answering Reviewers	5388-Answering reviewers.pdf
Copyright License Agreement	5388-Copyright assignment.pdf
Peer-review Report	5388-Peer review(s).pdf
Scientific Editor Work List	5388-Scientific editor work list.doc