Publication Name	World Journal of Gastroenterology
Manuscript ID	53980
Country	Italy

Received	2020-01-02 15:09
Peer-Review Started	2020-01-02 15:10
To Make the First Decision
Return for Revision	2020-03-21 23:29
Revised	2020-06-12 06:08
Second Decision	2020-06-15 08:56
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2020-06-15 18:10
Articles in Press	2020-06-15 18:10
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2020-06-19 00:47
Publish the Manuscript Online	2020-06-21 14:15

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright	© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Opinion Review
Article Title	Liver-directed therapies for liver metastases from neuroendocrine neoplasms: Can laser ablation play any role?
Manuscript Source	Invited Manuscript
All Author List	Sergio Sartori, Lara Bianchi, Francesca Di Vece and Paola Tombesi
ORCID	Author(s) ORCID Number Sergio Sartori http://orcid.org/0000-0002-5056-1004 Lara Bianchi http://orcid.org/0000-0002-7761-5877 Francesca Di Vece http://orcid.org/0000-0002-2710-9474 Paola Tombesi http://orcid.org/0000-0003-0535-840X
Funding Agency and Grant Number
Corresponding Author	Sergio Sartori, MD, Chief Doctor, Director, Department of Internal Medicine, Section of Interventional Ultrasound, St. Anna Hospital, Via A. Moro 8, Ferrara 44100, Italy. srs@unife.it
Key Words	Neuroendocrine neoplasms; Liver metastases; Liver-directed therapies; Ablation techniques; Laser ablation; Radiofrequency ablation
Core Tip	Laser ablation (LA) can be useful in the treatment of liver metastases (LM) from neuroendocrine neoplasms (NEN). The multi-fiber technique enables the use of one to four fibers at once, achieving ablation areas from one to 4-5 cm in diameter, and tailoring the size of each thermal lesion to that of each tumor, sparing the liver parenchyma more than any other liver-directed therapy. A recent retrospective study reporting the largest series of LM treated with LA documents both safety and effectiveness of LA, that can be added to the armory of the multimodality approach to LM from NEN.
Publish Date	2020-06-21 14:15
Citation	Sartori S, Bianchi L, Di Vece F, Tombesi P. Liver-directed therapies for liver metastases from neuroendocrine neoplasms: Can laser ablation play any role? World J Gastroenterol 2020; 26(23): 3118-3125
URL	https://www.wjgnet.com/1007-9327/full/v26/i23/3118.htm
DOI	https://dx.doi.org/10.3748/wjg.v26.i23.3118

Full Article (PDF)	WJG-26-3118.pdf
Full Article (Word)	WJG-26-3118.docx
Manuscript File	53980-Review.doc
Answering Reviewers	53980-Answering reviewers.pdf
Audio Core Tip	53980-Audio core tip.mp3
Conflict-of-Interest Disclosure Form	53980-Conflict-of-interest statement.pdf
Copyright License Agreement	53980-Copyright license agreement.pdf
Non-Native Speakers of English Editing Certificate	53980-Language certificate.pdf
Peer-review Report	53980-Peer-review(s).pdf
Scientific Misconduct Check	53980-Bing-Dou Y-2.png
Scientific Misconduct Check	53980-Scientific misconduct check.pdf
Scientific Editor Work List	53980-Scientific editor work list.pdf