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Articles Published Processes
9/28/2020 1:45:48 AM | Browse: 599 | Download: 1517
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Received |
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2020-01-17 15:17 |
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Peer-Review Started |
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2020-01-17 15:18 |
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To Make the First Decision |
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Return for Revision |
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2020-08-21 05:53 |
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Revised |
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2020-09-01 08:45 |
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Second Decision |
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2020-09-03 09:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2020-09-04 03:12 |
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Articles in Press |
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2020-09-04 03:12 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2020-09-09 02:56 |
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Typeset the Manuscript |
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2020-09-23 16:32 |
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Publish the Manuscript Online |
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2020-09-28 01:45 |
ISSN |
2307-8960 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Hematology |
Manuscript Type |
Case Report |
Article Title |
Therapy-related acute promyelocytic leukemia with FMS-like tyrosine kinase 3-internal tandem duplication mutation in solitary bone plasmacytoma: A case report
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Li-Li Hong, Xian-Fu Sheng and Hai-Feng Zhuang |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
Natural Science Foundation of Zhejiang Province |
LY19H290003 |
Zhejiang Provincial Medical and Health Science and Technology Project |
2020KY196 |
Foundation of Zhejiang Province Chinese Medicine Science and Technology Planes |
2017ZB030 |
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Corresponding Author |
Hai-Feng Zhuang, PhD, Associate Professor, Department of Hematology, The First Affiliated Hospital of Zhejiang Chinese Medical University, No 54 Youdian Road, Hangzhou 310000, Zhejiang Province, China. zhuanghaifeng@163.com |
Key Words |
Solitary bone plasmacytoma; Therapy-related acute promyelocytic; Leukemia; FMS-like tyrosine kinase 3-internal tandem duplication mutation; Radiotherapy; Cytopenia;Disseminated intravascular coagulation; Case report |
Core Tip |
We describe a 64-year-old woman presented with lumbar pain who was initially diagnosed as solitary bone plasmacytoma (SBP), while finally developed into acute promyelocytic leukemia (APL) with FMS-like tyrosine kinase 3-internal tandem duplication (FLT3-ITD) mutation after radiotherapy. To the best of our knowledge, this is the first report of t-APL with FLT3-ITD mutation in a patient with SBP treated with radiotherapy. The clinical outcomes of t-APL with FLT3-ITD mutation secondary to SBP after radiotherapy was poor. We should consider the potential risk of secondary neoplasms in SBP patients after radiotherapy. |
Publish Date |
2020-09-28 01:45 |
Citation |
Hong LL, Sheng XF, Zhuang HF. Therapy-related acute promyelocytic leukemia with FMS-like tyrosine kinase 3-internal tandem duplication mutation in solitary bone plasmacytoma: A case report. World J Clin Cases 2020; 8(19): 4579-4587 |
URL |
https://www.wjgnet.com/2307-8960/full/v8/i19/4579.htm |
DOI |
https://dx.doi.org/10.12998/wjcc.v8.i19.4579 |
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