| ISSN |
2307-8960 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Clinical and Translational Research |
| Article Title |
Cross electro-nape-acupuncture ameliorates cerebral hemorrhage-induced brain damage by inhibiting necroptosis
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Guo-Feng Cai, Zhong-Ren Sun, Zhe Zhuang, Hai-Chun Zhou, Shan Gao, Kai Liu, Li-Li Shang, Kun-Ping Jia, Xiu-Zhen Wang, Hui Zhao, Guo-Liang Cai, Wen-Li Song and Sheng-Nan Xu |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| State Administration of Traditional Chinese Medicine of Heilongjiang Province |
ZHY16-027 |
| Harbin Municipal Science and Technology Bureau-Youth Reserve Talent Project |
2017RAQXJ170 |
|
| Corresponding Author |
Kun-Ping Jia, MSc, Attending Doctor, Hanan Branch of Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, No. 26, Second Avenue, Pingfang District, Harbin 150001, Heilongjiang Province, China. jka3ih@163.com |
| Key Words |
Cross electro-nape acupuncture; Cerebral hemorrhage; Receptor interacting protein kinase 1; Necroptosis; Quantitative real time polymerase chain reaction; Enzyme linked immunosorbent assay |
| Core Tip |
This study uncovered that necroptosis existed in brain of rat with cerebral hemorrhage (CH). Further exploration revealed that receptor interacting protein kinase 1 (RIPK1) mediated necroptosis in CH, and cross electro-nape acupuncture (CENA) suppressed RIPK1 to ameliorate brain damage of rats with CH. Moreover, CENA could inhibit inflammation in CH. Therefore, these results suggested a neuroprotective role of CENA by targeting RIPK1-mediated necroptosis in rats with CH. |
| Publish Date |
2020-05-25 09:57 |
| Citation |
Cai GF, Sun ZR, Zhuang Z, Zhou HC, Gao S, Liu K, Shang LL, Jia KP, Wang XZ, Zhao H, Cai GL, Song WL, Xu SN. Cross electro-nape-acupuncture ameliorates cerebral hemorrhage-induced brain damage by inhibiting necroptosis. World J Clin Cases 2020; 8(10): 1848-1858 |
| URL |
https://www.wjgnet.com/2307-8960/full/v8/i10/1848.htm |
| DOI |
https://dx.doi.org/10.12998/wjcc.v8.i10.1848 |
