Publication Name	World Journal of Gastroenterology
Manuscript ID	5413
Country	Japan

Received	2013-09-06 13:56
Peer-Review Started	2013-09-06 18:29
To Make the First Decision	2013-09-27 16:54
Return for Revision	2013-09-29 10:33
Revised	2013-10-27 07:37
Second Decision	2013-11-18 21:01
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2013-11-19 12:18
Articles in Press
Publication Fee Transferred
Edit the Manuscript by Language Editor	2014-03-15 03:25
Typeset the Manuscript	2014-04-01 11:01
Publish the Manuscript Online	2014-04-17 13:27

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Autobiography
Article Title	Risk factors associated with Barrett’s epithelial dysplasia
Manuscript Source	Invited Manuscript
All Author List	Mikiko Fujita, Yuri Nakamura, Saeko Kasashima, Maiko Furukawa, Ryoichi Misaka and Hikaru Nagahara
Funding Agency and Grant Number
Corresponding Author	Hikaru Nagahara, Professor, Department of Gastroenterology, Aoyama Hospital, Tokyo Women’s Medical University, 2-7-13 Kitaaoyama, Minato-ku, Tokyo 1070061, Japan. nagahara.hikaru@twmu.ac.jp
Key Words	Barrett’s esophagus; Dysplasia; Helicobacter pylori; p53; Risk factors
Core Tip	Barrett’s esophagus (BE) is known to be a precancerous state of adenocarcinoma will become common in Asian countries, therefore, it is important to establish a high-risk group or strategy for screening or follow-up of BE. We present here the results of univariate and multivariate analysis to identify variables associated with dysplasia of BE. p53 expression in immunohistochemistry was associated with dysplasia, and Helicobacter pylori infection and high diastolic blood pressure may act as protective factors against dysplastic change of BE. These three factors may be candidates to establish a high-risk group for esophageal adenocarcinoma.
Publish Date	2014-04-17 13:27
Citation	Fujita M, Nakamura Y, Kasashima S, Furukawa M, Misaka R, Nagahara H. Risk factors associated with Barrett’s epithelial dysplasia. World J Gastroenterol 2014; 20(15): 4353-4361
URL	http://www.wjgnet.com/1007-9327/full/v20/i15/4353.htm
DOI	http://dx.doi.org/10.3748/wjg.v20.i15.4353

Full Article (PDF)	WJG-20-4353.pdf
Full Article (Word)	WJG-20-4353.doc
Manuscript File	5413-Review.docx
Answering Reviewers	5413-Answering reviewers.pdf
Copyright License Agreement	5413-Copyright assignment.pdf
Non-Native Speakers of English Editing Certificate	Editing_Certificate_20130905224431.pdf
Peer-review Report	5413-Peer review(s).pdf
Scientific Editor Work List	5413-Scientific editor work list.doc